88 Results for "

deep

" in MedChemExpress (MCE) Product Catalog:
Products (88)

88 Results for "deep" in MCE Product Catalog:

65
Crystal Violet
Crystal Violet
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65 Publications Verification
Cat. No.: HY-B0324A
CAS No.: 548-62-9
Synonyms: Basic Violet 3; Gentian Violet; Methyl Violet 10B
Crystal Violet, also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining[1].
14
MitoTracker Deep Red FM
MitoTracker Deep Red FM
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14 Cited Publications
Cat. No.: HY-D1783
CAS No.: 873315-86-7
Synonyms: MTDR FM
Target:  

Fluorescent Dye

Research Areas:  

Others

MitoTracker Deep Red (MTDR) FM fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Deep Red FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 644/665 nm . MitoTracker Deep Red dyes have an excitation/emission wavelength of 633/650-750 nm .
The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm.
9
Tetrazolium Red
Tetrazolium Red
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9 Cited Publications
Cat. No.: HY-D0714
CAS No.: 298-96-4
Synonyms: 2,3,5-Triphenyltetrazolium chloride; TPTZ; TTC
Tetrazolium Red (2,3,5-Triphenyltetrazolium chloride; TTC) is a not brain-penetrant, colorless, water-soluble dye that is reduced by mitochondrial enzymes to a deep red, water-insoluble compound (formazan) mainly in the mitochondria of living cells. Tetrazolium Red is used to observe the activity of dehydrogenase, and it turns colorless to red when exposed to hydrogen. Tetrazolium Red distinguishes between surviving and infarcted brain tissue after stroke. Tetrazolium Red has been used to stain heart tissue to measure the extent of acute lesions and also used to stain brain tissue to detect the size of the infarcted area. The absorption wavelength of Tetrazolium Red is 570 nm .
7
AkaLumine hydrochloride
AkaLumine hydrochloride
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7 Cited Publications
Cat. No.: HY-112641A
CAS No.: 2558205-28-8
Purity:  99.92%
AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
3
Cuprizone
Cuprizone
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3 Cited Publications
Cat. No.: HY-W115718
CAS No.: 370-81-0
Target:  

Dopamine β-hydroxylase

Research Areas:  

Neurological Disease

Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC) .
3
HBmito Crimson
HBmito Crimson
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3 Cited Publications
Cat. No.: HY-D2346
HBmito Crimson is a deep red fluorescent probe (λex: 658 nm, λem: 678 nm) for the inner mitochondrial membrane. HBmito Crimson is a cell membrane-permeable probe with high selectivity for the mitochondrial inner membrane, suitable for specific fluorescence staining of the inner mitochondrial membrane in living cells. HBmito Crimson has high photostability and brightness, suitable for long-term dynamic fluorescence imaging.
2
LL-37 amide
LL-37 amide
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2 Cited Publications
Cat. No.: HY-P4744
CAS No.: 597562-32-8
Target:  

Formyl Peptide Receptor (FPR) Bacterial

Research Areas:  

Infection Cancer

LL-37 amide is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED99=8.5-8.7 μg/mL). LL-37 amide exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .
2
NT-1
NT-1
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2 Cited Publications
Cat. No.: HY-13984
CAS No.: 1421373-62-7
Purity:  99.51%
Synonyms: EGFR mutant-IN-3
Target:  

EGFR ERK Apoptosis Drug Derivative

Research Areas:  

Cancer

NT-1 (EGFR mutant-IN-3) is a potent mutant EGFR inhibitor and an analog of Osimertinib (HY-15772). This mutant EGFR inhibitor suppresses FGFR WT with an IC50 of 0.4 nM. NT-1 also inhibits EGFR L858R, EGFR Exon 19 deletion and EGFR T790M. NT-1 exerts deeper inhibition on p-EGFR and p-ERK, and induces tumor cell apoptosis. NT-1 can be used in colorectal cancer research .
2
LL-37 amide TFA
LL-37 amide TFA
0 Images
2 Cited Publications
Cat. No.: HY-P4744A
Target:  

Formyl Peptide Receptor (FPR) Bacterial

Research Areas:  

Infection Cancer

LL-37 amide TFA is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED99=8.5-8.7 μg/mL). LL-37 amide TFA exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide TFA possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .
1
Acid Red 94 sodium
Acid Red 94 sodium
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1 Cited Publications
Cat. No.: HY-D0214
CAS No.: 632-69-9
Acid Red 94 sodium, a synthetic fluorescein derivative, is a deep red dye primarily composed of 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. It is widely used as an ophthalmic diagnostic agent to detect dry or damaged cells on the ocular surface. Acid Red 94 sodium exhibits antitumor activity and can inhibit Friend Leukemia Virus (FLV) infection through photodynamic action. Additionally, Acid Red 94 sodium can inhibit Aβ aggregation through light irradiation. Acid Red 94 sodium holds potential for use in cancer, viral infections, and neurodegenerative disease research .
1
Enoxaparin
Enoxaparin
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1 Cited Publications
Cat. No.: HY-109509
CAS No.: 679809-58-6
Synonyms: PK 10169; Enoxaparin sodium
Target:  

Factor Xa Thrombin SARS-CoV

Research Areas:  

Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer

Enoxaparin (PK 10169), a low-molecular-weight heparin (LMWH) derivative. Enoxaparin exerts anticoagulant activity through antithrombin III, an endogenous inhibitor of factor Xa and thrombin IIa. Enoxaparin protect the rat hippocampus against TBI (traumatic brain injury) via antioxidant and anti-inflammatory properties. Enoxaparin can be used for the research of deep vein thrombosis (DVT), pulmonary embolism, TBI and COVID-19 .
1
Carboxy-SNARF 1 (5/6-mixture)
Carboxy-SNARF 1 (5/6-mixture)
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1 Cited Publications
Cat. No.: HY-D1094
CAS No.: 126208-12-6
Synonyms: SNARF 1
Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH (Ex: 488 nm). Carboxy-SNARF 1 (5/6-mixture) can be used for measurement pH. Carboxy-SNARF 1 (5/6-mixture) exhibits a significant emission shift from yellow-orange (Em: 580 nm) to deep red fluorescence (Em: 640 nm) under acidic and basic conditions (pH=7-8), respectively .
1
DL-Panthenol
DL-Panthenol
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1 Cited Publications
Cat. No.: HY-B1024
CAS No.: 16485-10-2
Synonyms: DL-Pantothenol; DL-Pantothenyl alcohol
DL-Panthenol (DL-Pantothenol) is a precursor of pantothenic acid. DL-Panthenol easily penetrates the skin and has effects of deep moisturizing, promoting wound healing and anti-inflammation. DL-Panthenol can also be used as a hair conditioner in cosmetics. DL-Panthenol has low acute toxicity, non-sensitizing property, and no significant genotoxicity or reproductive and developmental toxicity. DL-Panthenol can be applied to the research of cosmetics .
1
M8-B
M8-B
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1 Cited Publications
Cat. No.: HY-110181
CAS No.: 883976-12-3
Purity:  99.89%
Target:  

TRP Channel

Research Areas:  

Metabolic Disease

M8-B is a potent transient receptor potential melastatin-8 (TRPM8) antagonist. M8-B blocks cold-induced and TRPM8-agonist-induced activation TRPM8 channels. M8-B decreases deep body temperature (Tb) .
1
Psoralen-triethylene glycol azide
Psoralen-triethylene glycol azide
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1 Cited Publications
Cat. No.: HY-163213
CAS No.: 1352815-11-2
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

Psoralen-triepthylene glycol azide is a compound used to probe the structure and conformation of RNA in living cells, using matching RNA crosslinking and deep sequencing or comradery methods .
1
Dimethyl Citric acid
Dimethyl Citric acid
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1 Cited Publications
Cat. No.: HY-N9542
CAS No.: 53798-97-3
Category:  

Ketones, Aldehydes, Acids Other Diseases Plants Actinidiaceae Disease Research Fields Actinidia arguta (Sieb. & Zucc) Planch. ex Miq.

Target:  

Others

Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.
1
Acid Red 94 sodium (80%)
Acid Red 94 sodium (80%)
0 Images
1 Cited Publications
Cat. No.: HY-D0214E
CAS No.: 632-69-9
Acid Red 94 sodium (80%), a synthetic fluorescein derivative, is a deep red dye primarily composed of 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Acid Red 94 sodium (80%) is widely used as an ophthalmic diagnostic agent to detect dry or damaged cells on the ocular surface. Acid Red 94 sodium (80%) exhibits antitumor activity and can inhibit Friend Leukemia Virus (FLV) infection through photodynamic action. Additionally, Acid Red 94 sodium (80%) can inhibit Aβ aggregation through light irradiation. Acid Red 94 sodium (80%) holds potential for use in cancer, viral infections, and neurodegenerative disease research .
Allura Red AC
Allura Red AC
0 Images
Cat. No.: HY-123630
CAS No.: 25956-17-6
Purity:  98.01%
Synonyms: FD&C RED NO. 40; CI 16035
Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine (5-HT) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety .
Celltrack Deep Red
Celltrack Deep Red
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Cat. No.: HY-D2865
Celltrack Deep Red is a fluorescent dye with a fluorescence signal that can be maintained for at least 72 h and has good stability. Celltrack Deep Red can be used for cell tracing and multi-generation cell movement tracking. Within a cell population, Celltrack Deep Red is only transferred to daughter cells and not to neighboring cells (Ex/Em = 630/650 nm) .
Aspartate aminotransferase, porcine heart
Aspartate aminotransferase, porcine heart
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Cat. No.: HY-P3016A
CAS No.: 9000-97-9
Synonyms: EC 2.6.1.1, porcine heart; GOT, porcine heart; AST, porcine heart
Target:  

Aminotransferases (Transaminases)

Research Areas:  

Cardiovascular Disease

Aspartate aminotransferase (EC 2.6.1.1), porcine heart is a metabolic regulator with the highest activity in the heart, liver and skeletal muscle. Aspartate aminotransferase, porcine heart comprises two isozymes: the cytoplasmic form (AST1) and the mitochondrial form (AST2). By catalyzing reversible transamination reactions between oxaloacetate, L-glutamate and other substances, it is deeply involved in key physiological processes such as amino acid metabolism, the tricarboxylic acid cycle and neurotransmitter synthesis. Aspartate aminotransferase, porcine heart also provides substrate support for the synthesis of urea and purines/pyrimidines. Aspartate aminotransferase, porcine heart is a serum marker reflecting cardiac and hepatic injury, and its abnormal levels are also closely associated with myocardial infarction, cardiovascular diseases and various cancers .
Assay Types