34 Results for "

diarylheptanoids

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "diarylheptanoids" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N9633
CAS No.: 87657-77-0
Oxyphyllacinol is a natural product that can be derived from the fruit of Alpinia oxyphylla .
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Cat. No.: HY-N0558
CAS No.: 33457-62-4
Alnustone, a non-phenolic diarylheptanoid found in herbs and spices, is a constituent of Alpiniae Katsumada. Alnustone displays anti-emetic and anti-inflammatory activities .
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Cat. No.: HY-N3225
CAS No.: 33606-81-4
Myricanol is a diarylheptanoid and a Nampt activator. Myricanol exerts anti-inflammatory effects and alleviates glucocorticoid-induced muscle atrophy by increasing Sirtuin 1 (SIRT1) and PRDX5 activities while regulating inflammatory factors. Myricanol exhibits growth inhibition and induces apoptosis in human lung adenocarcinoma A549 cells. Myricanol promotes autophagy-mediated clearance of microtubule-associated protein tau to exert neuroprotective effects. Myricanol protects cardiovascular function by inhibiting PDGFRβ and NF-κB signaling pathways. Myricanol activates mitochondrial transcription factor A (TFAM) expression to exert anti-renal fibrosis effects. Myricanol improves insulin resistance through AMPK activation .
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Cat. No.: HY-134650
CAS No.: 100667-52-5
(4E)-7-(4-Hydroxyphenyl)-1-phenylhept-4-en-3-one (Compound 8) is a diarylheptanoid containing two benzene rings. Diarylheptanoid is widely distributed in Alpinia, and exhibits cytotoxic, anti-inflammatory, antiplatelet, antioxidant, and antiproliferative activities .
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Cat. No.: HY-N10892
CAS No.: 1246282-67-6
Officinaruminane B (compound 2), a diarylheptanoid, is a nature product that could be isolated from the rhizome of Alpinia officinarum .
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Cat. No.: HY-N10158
CAS No.: 207792-17-4
Target:  

Drug Derivative

Research Areas:  

Cancer

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one (compound 39), a diarylheptanoid, exhibits antiproliferative activity towards human HT-1080 fibrosarcoma and murine colon 26-L5 carcinoma cells .
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Cat. No.: HY-N10405
CAS No.: 100761-20-4
(R)-5-Hydroxy-1,7-diphenyl-3-heptanone is a diarylheptanoid that can be found in Alpinia officinarum. (R)-5-Hydroxy-1,7-diphenyl-3-heptanone ameliorates oxidative stress and insulin resistance via activation of Nrf2/ARE pathway .
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Cat. No.: HY-N10890
CAS No.: 1041740-13-9
Alpinoid D, a diarylheptanoid, can be isolated from the MeOH extract from the rhizomes of Alpinia officinarum Hance. Alpinoid D shows cytotoxic effect against IMR-32 human neuroblastoma cell line .
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Cat. No.: HY-N4044
CAS No.: 41137-86-4
Synonyms: (5S)-Hirsutanonol
Hirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC50 value of 44.11 μg/mL for microfilariae .
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Cat. No.: HY-N16524
CAS No.: 2151847-03-7
Alpinin A is a diarylheptanoid found in the rhizomes of Alpinia officinarum. Alpinin A can strongly inhibit the aggregation of α-synuclein with inhibition rate of 66% at 10 μM. Alpinin A can be used for the research of neurological disease, such as Parkinson’s disease .
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Cat. No.: HY-N4042
CAS No.: 41137-87-5
Hirsutenone is an active botanical diarylheptanoid present in Alnus species and exhibits many biological activities, including anti-inflammatory, anti-tumor promoting and anti-atopic dermatitis effects. Hirsutenone attenuates adipogenesis by binding directly to PI3K and ERK1 in a non-ATP competitive manner. Hirsutenone can be used for the study of obesity .
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Cat. No.: HY-N15613
CAS No.: 408324-13-0
α-Synuclein inhibitor 14 (Compound 3) is a diarylheptanoid that can be isolated from Alpinia officinarum. α-Synuclein inhibitor 14 can inhibit the aggregation of α-synuclein, with an inhibition rate of 72.4% at a concentration of 10 μM. α-Synuclein inhibitor 14 can be used in the research of neurodegenerative diseases such as Parkinson's disease .
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Cat. No.: HY-N15215
CAS No.: 1004319-60-1
Antiviral agent 64 (Compound 12) is a diarylheptanoid that can be isolated from Alpinia officinarum. Antiviral agent 64 exhibits cytotoxicity in human neuroblastoma cell IMR-32 with an IC50 of 0.23 μM. Antiviral agent 64 exhibits antiviral efficacy, that inhibits RSV, poliovirus, measles virus, HSV-1, and influenza virus H1N1, with EC50 of 13.3, 3.7, 6.3, 5.7, and <10 μg/mL, respectively .
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Cat. No.: HY-N12362
CAS No.: 68622-73-1
Antiviral agent 41 (compound 5) is a diarylheptanoid isolated from Alpinia officinarum. Antiviral agent 41 exhibits potential antiviral activity against influenza virus in vitro .
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Cat. No.: HY-N15618
CAS No.: 87095-75-8
Antiviral agent 68 (Compound 3) is a diarylheptanoid that can be isolated from Alpinia katsumadai. Antiviral agent 68 has weak inhibitory activity against the neuraminidase of influenza virus A/PR/8/34, with an IC50 of 29.75 μM .
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Cat. No.: HY-N4043
CAS No.: 93915-36-7
Synonyms: Hirsutanonol 5-O-glucoside
Hirsutanonol 5-O-glucoside is a diarylheptanoid derivatives that can be isolated from Alnus hirsuta. Hirsutanonol 5-O-glucoside exhibits significant hepatoprotective effects against t-BHP-induced toxicity in HepG2 cells with 42.8% protection .
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Cat. No.: HY-N9093
CAS No.: 1269839-26-0
(3R,5R)-3,5-Diacetoxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane, a diarylheptanoid from the rhizomes of Curcuma kwangsiensis, possesses a variety of biological and pharmacological activities including antioxidant, antihepa totoxic, anti-inflammatory, antiproliferative, antiemetic, and antitumor activities .
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Cat. No.: HY-N8358
CAS No.: 473451-73-9
Carpinontriol B is a natural diarylheptanoid compound .
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Cat. No.: HY-N1536
CAS No.: 56222-03-8
Synonyms: (-)-Porson; Porson
Porsone (Porson) is a cyclic diarylheptanoid, that can be isolated from the roots of Myrica nana .
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Cat. No.: HY-N8975
CAS No.: 105955-04-2
Antitumor agent-137 (Compound M12) is a linear diarylheptanoid compound with antitumor activity .
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