3 Results for "

diarylpropionitrile

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "diarylpropionitrile" in MCE Product Catalog:

17
17 Cited Publications
Cat. No.: HY-12452
CAS No.: 1428-67-7
Purity:  99.66%
Synonyms: diarylpropionitrile
DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor β (ERβ) selective ligand, with an EC50 of 0.85 nM. DPN has neuroprotective effects in a number of neurological diseases .
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Cat. No.: HY-12452R
CAS No.: 1428-67-7
Synonyms: diarylpropionitrile (Standard)
DPN (Standard) is the analytical standard of DPN. This product is intended for research and analytical applications. DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor β (ERβ) selective ligand, with an EC50 of 0.85 nM. DPN has neuroprotective effects in a number of neurological diseases .
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Cat. No.: HY-103453
CAS No.: 524047-78-7
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

(R)-DPN (compound 3) is a selective ERβ ligand with EC50s of 2.9, 0.8 nM for ERα and ERβ, respectively. (R)-DPN shows a very high affinity and potency preference for ERβ over ERα. (R)-DPN shows cytoxicity for HEC-1 and U2OS cells with EC50s of 286, 205 nM, respectively .
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