524047-78-7
524047-78-7
Chemical Structure
(R)-DPN
- CAS No.: 524047-78-7
- Formula:C15H13NO2
- Molecular Weight:239.27
IUPAC Name: (R)-2,3-bis(4-hydroxyphenyl)propanenitrile
InChIKey: GHZHWDWADLAOIQ-ZDUSSCGKSA-N
SMILES: N#C[C@@H](C(C=C1)=CC=C1O)CC(C=C2)=CC=C2O
Biological Activity: (R)-DPN (compound 3) is a selective ERβ ligand with EC50s of 2.9, 0.8 nM for ERα and ERβ, respectively. (R)-DPN shows a very high affinity and potency preference for ERβ over ERα. (R)-DPN shows cytoxicity for HEC-1 and U2OS cells with EC50s of 286, 205 nM, respectively[1].
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(R)-DPN | (R)-DPN (compound 3) is a selective ERβ ligand with EC50s of 2.9, 0.8 nM for ERα and ERβ, respectively. (R)-DPN shows a very high affinity and potency preference for ERβ over ERα. (R)-DPN shows cytoxicity for HEC-1 and U2OS cells with EC50s of 286, 205 nM, respectively. | |||||||||||||||||||||
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References
Keywords
