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Results for "

dibutyryl cyclic adenosine 3',5'-monophosphate

" in MedChemExpress (MCE) Product Catalog:

2242

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14

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78

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504

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10

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370

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47

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208

Isotope-Labeled Compounds

45

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28

Click Chemistry

278

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4

GMP Molecules

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0764
    Bucladesine sodium
    40+ Cited Publications

    dibutyryl cAMP sodium; DBcAMP sodium

    		 PKA Reactive Oxygen Species (ROS) Apoptosis Neurological Disease Inflammation/Immunology Cancer
    Bucladesine (Dibutyryl cAMP; DBcAMP) sodium is a membrane-permeable 3′, 5′-cyclic adenosine monophosphate (cAMP) analog. Bucladesine selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP. Bucladesine significantly attenuates MDMA-induced increases in hippocampal mitochondrial ROS formation, mitochondrial outer membrane damage, cytochrome c release, and hippocampal ADP/ATP ratio, thereby improving spatial learning and memory impairments. Bucladesine exhibit anti-nociceptive and anti-inflammation effect. Bucladesine can inhibit cancer cells proliferation, induce apoptosis. Bucladesine can be used for the researches of neurological disease, cancer, inflammation [3] .
    Bucladesine sodium
  • HY-B1511
    Cyclic AMP
    20+ Cited Publications

    cyclic adenosine monophosphate; adenosine cyclic 3', 5'-monophosphate; cAMP

    		 Endogenous Metabolite Neurological Disease Metabolic Disease Cancer
    Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes [3].
    Cyclic AMP
  • HY-A0181
    Adenosine monophosphate
    15+ Cited Publications

    AMP

    		 Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [3].
    Adenosine monophosphate
  • HY-B1511A
    Cyclic AMP sodium
    20+ Cited Publications

    cyclic adenosine monophosphate sodium; adenosine cyclic 3', 5'-monophosphate sodium; cAMP sodium

    		 Biochemical Assay Reagents Neurological Disease Metabolic Disease Cancer
    Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes [3].
    Cyclic AMP sodium
  • HY-B0764A
    Bucladesine hemicalcium
    40+ Cited Publications

    dibutyryl cAMP hemicalcium; DBcAMP hemicalcium

    		 PKA Apoptosis Reactive Oxygen Species (ROS) Neurological Disease Cancer
    Bucladesine (Dibutyryl cAMP; DBcAMP) hemicalcium is a membrane-permeable 3′, 5′-cyclic adenosine monophosphate (cAMP) analog. Bucladesine selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP. Bucladesine significantly attenuates MDMA-induced increases in hippocampal mitochondrial ROS formation, mitochondrial outer membrane damage, cytochrome c release, and hippocampal ADP/ATP ratio, thereby improving spatial learning and memory impairments. Bucladesine exhibit anti-nociceptive and anti-inflammation effect. Bucladesine can inhibit cancer cells proliferation, induce apoptosis. Bucladesine can be used for the researches of neurological disease, cancer, inflammation [3] .
    Bucladesine hemicalcium
  • HY-12326
    c-di-AMP

    cyclic diadenylate; cyclic-di-AMP

    		 STING Bacterial Endogenous Metabolite Inflammation/Immunology
    c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humoral and cellular responses [3] .
    c-di-AMP
  • HY-W011256
    Adenosine 2',3'-cyclic phosphate sodium

    		Endogenous Metabolite Adenosine Deaminase Metabolic Disease
    Adenosine 2',3'-cyclic phosphate sodium is a 2',3'-cyclic purine nucleotide. Adenosine 2',3'-cyclic phosphate sodium is deaminated by the adenosine deaminase. Adenosine 2',3'-cyclic phosphate sodium can be degrade to 2'-AMP and 3'-AMP [3].
    Adenosine 2',3'-cyclic phosphate sodium
  • HY-P10033
    SFTI-1

    		Ser/Thr Protease Others
    SFTI-1 is a cyclic peptide trypsin inhibitor consisting of 14 amino acid residues. SFTI-1 belongs to the Bowman-Birk class of inhibitors. Characterized by its small size, high stability, and potent activity, SFTI-1 can be used for research on peptide drug design platforms .
    SFTI-1
  • HY-N0113
    Hordenine
    1 Publications Verification

    Ordenina; Peyocactine

    		 Bacterial Antibiotic Infection Cardiovascular Disease
    Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .
    Hordenine
  • HY-W587488
    Adenosine 3′-monophosphate

    3′-AMP

    		 Nucleoside Antimetabolite/Analog Cyclic GMP-AMP Synthase Cancer
    Adenosine 3’-monophosphate (3’-AMP) is a nucleotide. Adenosine 3’-monophosphate is a cyclic AMP production agonist. Adenosine 3’-monophosphate increases cyclic AMP levels concentration-dependently in NG108-15 cells. Adenosine 3’-monophosphate can be used in the determination of acid phosphatase activity of human serum, which is estabilished as a laboratory procedure in the diagnosis of prostate cancer, metastatic mammary cancer and Gaucher’s disease. Adenosine 3’-monophosphate inhibits human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors [3].
    Adenosine 3′-monophosphate
  • HY-B1511S
    Cyclic AMP-13C5

    cyclic adenosine monophosphate-13C5; adenosine cyclic 3', 5'-monophosphate-13C5; cAMP-13C5

    		 Isotope-Labeled Compounds Others
    Cyclic AMP- 13C5 is a deuterated cyclic AMP.
    Cyclic AMP-13C5
  • HY-103237
    L-Adenosine

    		Adenosine Deaminase Neurological Disease
    L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation .
    L-Adenosine
  • HY-W016009
    2'-Deoxyadenosine-5'-monophosphate

    		Endogenous Metabolite Metabolic Disease
    2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
    2'-Deoxyadenosine-5'-monophosphate
  • HY-111673
    8-CPT-Cyclic AMP sodium

    8-CPT-cAMP sodium; 8-(p-Chlorophenylthio)-cAMP sodium

    		 PKA Phosphodiesterase (PDE) Inflammation/Immunology
    8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). 8-CPT-Cyclic AMP sodium is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. 8-CPT-Cyclic AMP sodium also inhibits PDE III and PDE IV with IC50Cyclic AMP sodium is a very high affinity for Epac and is a potent Epac activator .
    8-CPT-Cyclic AMP sodium
  • HY-W011012
    Adenosine 5'-monophosphate disodium
    15+ Cited Publications

    		 Adenosine Receptor Metabolic Disease
    Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes [3].
    Adenosine 5'-monophosphate disodium
  • HY-A0181R
    Adenosine monophosphate (Standard)

    AMP (Standard)

    		 Reference Standards Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Adenosine monophosphate (Standard) is the analytical standard of Adenosine monophosphate (HY-A0181). This product is intended for research and analytical applications. Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [3].
    Adenosine monophosphate (Standard)
  • HY-A0181A
    Adenosine 5'-monophosphate monohydrate
    15+ Cited Publications

    5'-AMP monohydrate

    		 Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2 [3].
    Adenosine 5'-monophosphate monohydrate
  • HY-A0181S1
    Adenosine monophosphate-15N5 dilithium

    		Isotope-Labeled Compounds Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Adenosine monophosphate- 15N5 dilithium is the 15N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [3].
    Adenosine monophosphate-15N5 dilithium
  • HY-A0181S
    Adenosine monophosphate-13C10,15N5 dilithium

    AMP-13C10,15N5 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Adenosine monophosphate- 13C10, 15N5(AMP- 13C10, 15N5) is the 13C-labeled and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [3].
    Adenosine monophosphate-13C10,15N5 dilithium
  • HY-137243
    Adenosine 3',5'-diphosphate disodium

    		Endogenous Metabolite Nucleoside Antimetabolite/Analog Others
    Adenosine 3',5'-diphosphate disodium is an endogenous purine nucleotide. Adenosine 3',5'-diphosphate disodium acts as an inhibitor of bovine adrenal estrogen sulfotransferase (EST) with a Ki value of 7.0 μM. It also serves as an indispensable specific cofactor for the pregnenolone-binding protein (PBP) steroid-binding complex, with an EC50 value of 1.5 μM in guinea pigs .
    Adenosine 3',5'-diphosphate disodium
  • HY-P99169
    Uliledlimab

    TJ004309

    		 CD73 Cancer
    Uliledlimab is a potent against CD73 humanizedized monoclonal antibody. Uliledlimab inhibits the conversion of extracellular adenosine monophosphate (AMP) to adenosine. Uliledlimab can be used in research of cancer .
    Uliledlimab
  • HY-111926
    N6-Methyladenosine 5'-monophosphate disodium salt
    3 Publications Verification

    		 Biochemical Assay Reagents Others
    N6-Methyladenosine 5'-monophosphate disodium salt is an N6-methyladenosine derivative and also the phosphorylated form of N 6-methyladenosine. N6-Methyladenosine 5'-monophosphate disodium salt serves as an elution reagent for m6A-modified RNA in MeRIP assays [3].
    N6-Methyladenosine 5'-monophosphate disodium salt
  • HY-124151
    Adenosine-2'-monophosphate

    2'-AMP; adenosine 2'-phosphate; AMP 2'-phosphate

    		 Adenosine Receptor Endogenous Metabolite Neurological Disease
    Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2’,3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2’,3’-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A2A receptor activation .
    Adenosine-2'-monophosphate
  • HY-B1511R
    Cyclic AMP (Standard)

    cyclic adenosine monophosphate (Standard); adenosine cyclic 3', 5'-monophosphate (Standard); cAMP (Standard)

    		 Endogenous Metabolite Reference Standards Cancer
    Cyclic AMP (Standard) is the analytical standard of Cyclic AMP. Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes [3].
    Cyclic AMP (Standard)
  • HY-W250153
    Adenosine 3'-phosphate 5'-phosphosulfate lithium

    		P2Y Receptor Cardiovascular Disease
    Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group [3].
    Adenosine 3'-phosphate 5'-phosphosulfate lithium
  • HY-114175A
    Adenosine deaminase, Calf Spleen

    RnADA, Calf Spleen

    		 Adenosine Deaminase Inflammation/Immunology
    Adenosine deaminase, Calf Spleen is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively .
    Adenosine deaminase, Calf Spleen
  • HY-164090
    Adenosine 3'-phosphate 5'-phosphosulfate

    		P2Y Receptor Cardiovascular Disease
    Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group [3].
    Adenosine 3'-phosphate 5'-phosphosulfate
  • HY-B0764B
    Bucladesine

    dibutyryl cAMP; DBcAMP

    		 PKA Reactive Oxygen Species (ROS) Apoptosis Neurological Disease Inflammation/Immunology Cancer
    Bucladesine (Dibutyryl cAMP; DBcAMP) is a membrane-permeable 3′, 5′-cyclic adenosine monophosphate (cAMP) analog. Bucladesine selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP. Bucladesine significantly attenuates MDMA-induced increases in hippocampal mitochondrial ROS formation, mitochondrial outer membrane damage, cytochrome c release, and hippocampal ADP/ATP ratio, thereby improving spatial learning and memory impairments. Bucladesine exhibit anti-nociceptive and anti-inflammation effect. Bucladesine can inhibit cancer cells proliferation, induce apoptosis. Bucladesine can be used for the researches of neurological disease, cancer, inflammation [3] .
    Bucladesine
  • HY-W105272
    2′-Deoxyadenosine 5′-monophosphate disodium

    		Endogenous Metabolite Metabolic Disease
    2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
    2′-Deoxyadenosine 5′-monophosphate disodium
  • HY-131763
    2'-O-MB-cAMP sodium

    2'-O-Monobutyryl cyclic AMP sodium

    		 Drug Intermediate Others
    2'-O-MB-cAMP (2'-O-Monobutyryl cyclic AM) sodium is an activatable proagent of Cyclic AMP (HY-B1511) .
    2'-O-MB-cAMP sodium
  • HY-173593
    Adenosine-3',5'-bisphosphate

    		Small Interfering RNA (siRNA) Cancer
    Adenosine-3',5'-bisphosphate is an exoribonuclease XRN1 inhibitor with an IC50 of 36 nM, a KD of 12 nM, and a KD of 14 nM against human XRN2. Adenosine-3',5'-bisphosphate binds to the bimetallic active site of human XRN1, and also binds potently to human XRN2 via its conserved bimetallic active site. Adenosine-3',5'-bisphosphate can be used in research related to non-small cell lung cancer .
    Adenosine-3',5'-bisphosphate
  • HY-B0764G
    Bucladesine sodium

    dibutyryl cAMP sodium; DBcAMP sodium

    		 PKA Reactive Oxygen Species (ROS) Apoptosis Neurological Disease Inflammation/Immunology Cancer
    Bucladesine (Dibutyryl cAMP; DBcAMP) sodium (GMP) is a Bucladesine sodium (HY-B0764) produced by using GMP guidelines. Bucladesine (Dibutyryl cAMP; DBcAMP) is a membrane-permeable 3′, 5′-cyclic adenosine monophosphate (cAMP) analog. Bucladesine selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP. Bucladesine significantly attenuates MDMA-induced increases in hippocampal mitochondrial ROS formation, mitochondrial outer membrane damage, cytochrome c release, and hippocampal ADP/ATP ratio, thereby improving spatial learning and memory impairments. Bucladesine exhibit anti-nociceptive and anti-inflammation effect. Bucladesine can inhibit cancer cells proliferation, induce apoptosis. Bucladesine can be used for the researches of neurological disease, cancer, inflammation [3] .
    Bucladesine sodium
  • HY-A0181S3
    Adenosine monophosphate-13C10 dilithium

    AMP-13C10 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Adenosine monophosphate- 13C10 (AMP- 13C10) dilithium is 13C-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [3].
    Adenosine monophosphate-13C10 dilithium
  • HY-W654041
    Adenosine monophosphate-13C5

    AMP-13C5

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Adenosine monophosphate- 13C5 (AMP- 13C5) is 13C labeled Adenosine monophosphate. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
    Adenosine monophosphate-13C5
  • HY-W010968
    5'-Adenylic acid sodium hydrate
    15+ Cited Publications

    A-5'-P sodium hydrate; AMP sodium hydrate; adenosine 5'-monophosphate sodium hydrate

    		 Environmental Pollutants Biochemical Assay Reagents Others
    5'-Adenylic acid (sodium hydrate) (A-5'-P (sodium hydrate); AMP (sodium hydrate); Adenosine 5'-monophosphate (sodium hydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    5'-Adenylic acid sodium hydrate
  • HY-130354
    Dibutyryl-cGMP sodium
    2 Publications Verification

    Bt2cGMP sodium

    		 Potassium Channel Cardiovascular Disease
    Dibutyryl-cGMP sodium (Bt2cGMP sodium) is a cell-permeable cGMP analogue. Dibutyryl-cGMP sodium preferentially activates cGMP-dependent protein kinase (PKG). Dibutyryl-cGMP sodium inhibits the release of [ 3H]-arachidonic acid from γ thrombin-stimulated human platelets. Dibutyryl-cGMP sodium induces peripheral antinociception via activation of ATP-sensitive K + channels [3].
    Dibutyryl-cGMP sodium
  • HY-113606
    Adenosine 5'-phosphosulfate disodium

    		Drug Intermediate Metabolic Disease
    Adenosine 5'-phosphosulfate disodium is a metabolism intermediates of sulfur. Adenosine 5'-phosphosulfate disodium can used in study sulfotransferases and sulforeductases in various organisms .
    Adenosine 5'-phosphosulfate disodium
  • HY-P1949A
    Cyclic MKEY TFA

    		CXCR Cardiovascular Disease Cancer
    Cyclic MKEY TFA is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY TFA also protects against stroke-induced brain injury in mice .
    Cyclic MKEY TFA
  • HY-W011012S2
    Adenosine-5'-monophosphate-15N5 disodium

    		Isotope-Labeled Compounds Others
    Adenosine-5'-monophosphate- 15N5 (disodium) is the deuterium labeled Adenosine 5'-monophosphate disodium salt .
    Adenosine-5'-monophosphate-15N5 disodium
  • HY-113401
    Adenosine 2',3'-cyclic phosphate

    		Endogenous Metabolite Metabolic Disease
    Adenosine 2',3'-cyclic phosphate is a 2',3'-cyclic purine nucleotide. Adenosine 2',3'-cyclic phosphate can be degrade to 2'-AMP and 3'-AMP .
    Adenosine 2',3'-cyclic phosphate
  • HY-A0181S2
    Adenosine monophosphate-d12 dilithium

    AMP-d12 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Adenosine monophosphate-d12 (AMP-d12) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [3].
    Adenosine monophosphate-d12 dilithium
  • HY-B0764R
    Bucladesine sodium (Standard)

    dibutyryl cAMP sodium (Standard); DBcAMP sodium (Standard)

    		 Reference Standards PKA Reactive Oxygen Species (ROS) Apoptosis Neurological Disease Inflammation/Immunology Cancer
    Bucladesine (Dibutyryl cAMP; DBcAMP) sodium (Standard) is the analytical standard of Bucladesine sodiumn (HY-B0764). This product is intended for research and analytical applications. Bucladesine is a membrane-permeable 3′, 5′-cyclic adenosine monophosphate (cAMP) analog. Bucladesine selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP. Bucladesine significantly attenuates MDMA-induced increases in hippocampal mitochondrial ROS formation, mitochondrial outer membrane damage, cytochrome c release, and hippocampal ADP/ATP ratio, thereby improving spatial learning and memory impairments. Bucladesine exhibit anti-nociceptive and anti-inflammation effect. Bucladesine can inhibit cancer cells proliferation, induce apoptosis. Bucladesine can be used for the researches of neurological disease, cancer, inflammation [3] .
    Bucladesine sodium (Standard)
  • HY-134375
    cAIMP

    cyclic adenosine-Inosine monophosphate

    		 NF-κB IFNAR Inflammation/Immunology
    cAIMP (Cyclic Adenosine-Inosine Monophosphate) is an effective synthetic cyclic dinucleotide. cAIMP activates IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). cAIMP induces the secretion of IFNs and pro-inflammatory cytokines in vitro in human blood, with an EC50 of 6.4 μmol/L .
    cAIMP
  • HY-W016009R
    2'-Deoxyadenosine-5'-monophosphate (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    2'-Deoxyadenosine-5'-monophosphate (Standard) is the analytical standard of 2'-Deoxyadenosine-5'-monophosphate. This product is intended for research and analytical applications. 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
    2'-Deoxyadenosine-5'-monophosphate (Standard)
  • HY-D2361
    Adenosine 2'-PEG-Biotin

    		Nucleoside Antimetabolite/Analog Others
    Adenosine 2'-PEG-Biotin is a biochemical reagent derived from adenosine. Adenosine 2'-PEG-Biotin regulates cell signaling pathways by mimicking the effects of endogenous adenosine and binding to its receptors. Adenosine 2'-PEG-Biotin can be used in the research of bioprobes, biosensors and diagnostic reagents .
    Adenosine 2'-PEG-Biotin
  • HY-N0113B
    Hordenine hydrochloride
    1 Publications Verification

    Ordenina hydrochloride; Peyocactine hydrochloride

    		 Bacterial Infection
    Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .
    Hordenine hydrochloride
  • HY-W011012S
    Adenosine 5'-monophosphate-13C disodium

    		Isotope-Labeled Compounds Others
    Adenosine 5'-monophosphate- 13C (disodium) is a 13C-labeled Adenosine 5'-monophosphate (HY-W011012). Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes [3].
    Adenosine 5'-monophosphate-13C disodium
  • HY-N9422
    Adenosine 3'-phosphate 5'-phosphosulfate triethylamine

    		P2Y Receptor Cardiovascular Disease
    Adenosine 3'-phosphate 5'-phosphosulfate triethylamine, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group [3].
    Adenosine 3'-phosphate 5'-phosphosulfate triethylamine
  • HY-P3193A
    Cyclic nona-L-arginine hydrochloride

    		Biochemical Assay Reagents Others
    Cyclic nona-L-arginine hydrochloride, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .
    Cyclic nona-L-arginine hydrochloride
  • HY-A0181S6
    Adenosine monophosphate3C10,15N5

    AMP-13C10,15N5

    		 Isotope-Labeled Compounds Endogenous Metabolite Adenosine Receptor HSV Infection
    Adenosine monophosphate- 13C10, 15N5 (AMP- 13C10, 15N5) is the 13C- and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [3].
    Adenosine monophosphate3C10,15N5

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