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  3. Cucurbit[7]uril

Cucurbit[7]uril  (Synonyms: CB7; Carrier CB7)

Cat. No.: HY-104086 Purity: ≥95.0%
COA Handling Instructions

Cucurbit[7]uril is a cyclic organic molecule consisting of seven glycoluril units linked by methylene bridges. It has a rigid barrel-like structure with two identical inlets at both ends to selectively encapsulate guest molecules of appropriate size, shape, and polarity. Cucurbit[7]uril is known for its high binding affinity for a variety of organic and inorganic guests, including drugs, amino acids, peptides, and metal ions. This property makes them promising candidates for various applications in areas such as drug delivery, catalysis, and sensing.

For research use only. We do not sell to patients.

Cucurbit[7]uril Chemical Structure

Cucurbit[7]uril Chemical Structure

CAS No. : 259886-50-5

Size Price Stock Quantity
25 mg USD 80 In-stock
50 mg USD 130 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Cucurbit[7]uril is a cyclic organic molecule consisting of seven glycoluril units linked by methylene bridges. It has a rigid barrel-like structure with two identical inlets at both ends to selectively encapsulate guest molecules of appropriate size, shape, and polarity. Cucurbit[7]uril is known for its high binding affinity for a variety of organic and inorganic guests, including drugs, amino acids, peptides, and metal ions. This property makes them promising candidates for various applications in areas such as drug delivery, catalysis, and sensing.

In Vitro

Cucurbit[7]uril is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1162.96

Formula

C42H42N28O14

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1N(CN(C2=O)[C@]([C@@]3([H])N2CN(C4=O)[C@]([C@@]5([H])N4CN(C6=O)[C@]([C@@]7([H])N6CN8[C@]9([H])N%10C%11=O)([H])N(C(N7C%10)=O)CN%125)([H])N(C%12=O)CN3C%13=O)([H])N%13CN%14%15)[C@]%14([H])[C@]%16([H])N1CN(C%17=O)[C@@]([C@]%18([H])N%17CN(C%19=O)[C@@]([C@]%20([H])N%19CN(C8=O)[C@@]9([H])N%11CN%21%20)([H])N(C%21=O)CN%18C%22=O)([H])N%22CN%16C%15=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (42.99 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8599 mL 4.2994 mL 8.5987 mL
5 mM 0.1720 mL 0.8599 mL 1.7197 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥95.0%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.8599 mL 4.2994 mL 8.5987 mL 21.4969 mL
5 mM 0.1720 mL 0.8599 mL 1.7197 mL 4.2994 mL
10 mM 0.0860 mL 0.4299 mL 0.8599 mL 2.1497 mL
15 mM 0.0573 mL 0.2866 mL 0.5732 mL 1.4331 mL
20 mM 0.0430 mL 0.2150 mL 0.4299 mL 1.0748 mL
25 mM 0.0344 mL 0.1720 mL 0.3439 mL 0.8599 mL
30 mM 0.0287 mL 0.1433 mL 0.2866 mL 0.7166 mL
40 mM 0.0215 mL 0.1075 mL 0.2150 mL 0.5374 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cucurbit[7]uril Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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