Dasatinib derivative 1
Based on 1 Customer Validation
Dasatinib derivative 1 (2e) effectively releases NO and increases the concentration of 3′,5′-cyclic guanosine monophosphate, as well as maintains senolytic activity. Dasatinib derivative 1 (2e) can be used in the research for chronic ocular hypertension (COHT) glaucoma.
For research use only. We do not sell to patients.
- Purity: 99.74%
- CAS No.: 3079237-53-6
- Formula: C41H54ClN9O20S5
- Molecular Weight:1188.69
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 3079237-53-6
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Appearance Solid
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Molecular Weight 1188.69
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Formula C41H54ClN9O20S5
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Color White to off-white
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SMILES
O=S(C1=[N+](ON=C1OCCOCCOC(CCC(OCCN2CCN(CC2)C3=NC(C)=NC(NC4=NC=C(S4)C(NC5=C(C=CC=C5Cl)C)=O)=C3)=O)=O)[O-])(C6=CC=CC=C6)=O.OS(=O)(C)=O.OS(=O)(C)=O.OS(=O)(C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (42.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8413 mL | 4.2063 mL | 8.4126 mL | 21.0316 mL |
| 5 mM | 0.1683 mL | 0.8413 mL | 1.6825 mL | 4.2063 mL | |
| 10 mM | 0.0841 mL | 0.4206 mL | 0.8413 mL | 2.1032 mL | |
| 15 mM | 0.0561 mL | 0.2804 mL | 0.5608 mL | 1.4021 mL | |
| 20 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 1.0516 mL | |
| 25 mM | 0.0337 mL | 0.1683 mL | 0.3365 mL | 0.8413 mL | |
| 30 mM | 0.0280 mL | 0.1402 mL | 0.2804 mL | 0.7011 mL | |
| 40 mM | 0.0210 mL | 0.1052 mL | 0.2103 mL | 0.5258 mL |