1. Anti-infection
  2. Influenza Virus
  3. β-Cyclodextrin

β-Cyclodextrin  (Synonyms: Betadex)

Cat. No.: HY-107201 Purity: ≥98.0%
COA Handling Instructions

β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.

For research use only. We do not sell to patients.

β-Cyclodextrin Chemical Structure

β-Cyclodextrin Chemical Structure

CAS No. : 7585-39-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 33 In-stock
Solution
10 mM * 1 mL in Water USD 33 In-stock
Solid
10 g USD 30 In-stock
25 g USD 60 In-stock
50 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE β-Cyclodextrin

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.

In Vitro

β-Cyclodextrin (Beta-cyclodextrin; β-CD) is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds, which presents a hydrophilic external surface and a hydrophobic internal cavity[1]. In the pharmaceutical industry, β-Cyclodextrin (β-CD) has often been used to enhance the solubility of drugs, such as indomethacin, naringin, celecoxib, and citric acid[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1134.98

Formula

C42H70O35

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@]2([H])[C@@H]([C@@H](O)[C@](O[C@]3([H])[C@H](O[C@@](O[C@]4([H])[C@H](O[C@@](O[C@]5([H])[C@H](O[C@@](O[C@@]6([H])[C@H](O)[C@@H](O)[C@@](O[C@@H]6CO)([H])O[C@@]7([H])[C@H](O)[C@@H](O)[C@@](O[C@@H]7CO)([H])O[C@@]8([H])[C@H](O)[C@@H](O)[C@@](O[C@@H]8CO)([H])O2)([H])[C@H](O)[C@H]5O)CO)([H])[C@H](O)[C@H]4O)CO)([H])[C@H](O)[C@H]3O)CO)([H])O1)O

Structure Classification
Initial Source

Bacillus

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 38.75 mg/mL (34.14 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8811 mL 4.4054 mL 8.8107 mL
5 mM 0.1762 mL 0.8811 mL 1.7621 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.8811 mL 4.4054 mL 8.8107 mL 22.0268 mL
5 mM 0.1762 mL 0.8811 mL 1.7621 mL 4.4054 mL
10 mM 0.0881 mL 0.4405 mL 0.8811 mL 2.2027 mL
15 mM 0.0587 mL 0.2937 mL 0.5874 mL 1.4685 mL
20 mM 0.0441 mL 0.2203 mL 0.4405 mL 1.1013 mL
25 mM 0.0352 mL 0.1762 mL 0.3524 mL 0.8811 mL
30 mM 0.0294 mL 0.1468 mL 0.2937 mL 0.7342 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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β-Cyclodextrin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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β-Cyclodextrin
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