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  3. β-Cyclodextrin

β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.

For research use only. We do not sell to patients.

CAS No. : 7585-39-9

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Customer Review

Based on 9 publication(s) in Google Scholar

Other Forms of β-Cyclodextrin:

Top Publications Citing Use of Products

    β-Cyclodextrin purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Aug 11:34:102179.  [Abstract]

    β-Cyclodextrin (β-CD) (0-15 mM; 10 mL; 36 h; 37 ± 2 ℃) substantially enhanced the solubility of BRZ in PBS.

    β-Cyclodextrin purchased from MedChemExpress. Usage Cited in: Cell Rep. 2024 Nov 9;43(11):114962.  [Abstract]

    β-Cyclodextrin (β-CD) (5 mM; 6 h) counteracted the promoted ratio of CD4+IFN-γ+ cells and CD4+GZMB+ cells induced by depletion of Zdhhc3 in Hep1-6 cells.
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    • Customer Review

    Description

    β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.

    In Vitro

    β-Cyclodextrin (Beta-cyclodextrin; β-CD) is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds, which presents a hydrophilic external surface and a hydrophobic internal cavity[1]. In the pharmaceutical industry, β-Cyclodextrin (β-CD) has often been used to enhance the solubility of drugs, such as indomethacin, naringin, celecoxib, and citric acid[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Molecular Weight

    1134.98

    Formula

    C42H70O35

    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    OC[C@@H]1[C@]2([H])[C@@H]([C@@H](O)[C@](O[C@]3([H])[C@H](O[C@@](O[C@]4([H])[C@H](O[C@@](O[C@]5([H])[C@H](O[C@@](O[C@@]6([H])[C@H](O)[C@@H](O)[C@@](O[C@@H]6CO)([H])O[C@@]7([H])[C@H](O)[C@@H](O)[C@@](O[C@@H]7CO)([H])O[C@@]8([H])[C@H](O)[C@@H](O)[C@@](O[C@@H]8CO)([H])O2)([H])[C@H](O)[C@H]5O)CO)([H])[C@H](O)[C@H]4O)CO)([H])[C@H](O)[C@H]3O)CO)([H])O1)O

    Initial Source

    Bacillus

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 2 years
    -20°C 1 year
    Solvent & Solubility
    In Vitro: 

    H2O : 7 mg/mL (6.17 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 0.8811 mL 4.4054 mL 8.8107 mL
    5 mM 0.1762 mL 0.8811 mL 1.7621 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.95%

    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 0.8811 mL 4.4054 mL 8.8107 mL 22.0268 mL
    5 mM 0.1762 mL 0.8811 mL 1.7621 mL 4.4054 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    β-Cyclodextrin
    Cat. No.:
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