KRP-203 monophosphate
KRP-203 monophosphate is a monophosphate of KRP-203 (HY-13660). KRP-203 is an orally active sphingosine-1-phosphate receptor (S1PR) modulator that blocks the signal required by T cells to egress from lymph nodes and other lymphoid organs.
For research use only. We do not sell to patients.
- CAS No.: 749262-82-6
- Formula: C24H27ClNO6PS
- Molecular Weight:523.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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S1PR1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
117 nM
Compound: 5, KRP-203P
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Agonist activity at S1P1 receptor (unknown origin) expressed in CHO cells preincubated for 2 hrs followed by D2-labeled IP1 and Ab-Cryp addition measured after 1 hr by fluorescence assay
Agonist activity at S1P1 receptor (unknown origin) expressed in CHO cells preincubated for 2 hrs followed by D2-labeled IP1 and Ab-Cryp addition measured after 1 hr by fluorescence assay
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10.1039/C3MD00079F |
Chemical Information
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CAS No. 749262-82-6
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Molecular Weight 523.97
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Formula C24H27ClNO6PS
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SMILES
O=P(O)(OCC(CO)(CCC1=CC=C(C=C1Cl)SC2=CC(OCC3=CC=CC=C3)=CC=C2)N)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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