1. GPCR/G Protein
    Neuronal Signaling
  2. MCHR1 (GPR24)
  3. MCH(human, mouse, rat)

MCH(human, mouse, rat) 

Cat. No.: HY-P1205
Handling Instructions

MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively.

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MCH(human, mouse, rat) Chemical Structure

MCH(human, mouse, rat) Chemical Structure

CAS No. : 128315-56-0

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Description

MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1].

IC50 & Target

Binding IC50: 0.3 nM (MCH1R)
IC50: 1.5 nM (MCH1R)[1]

Molecular Weight

2386.84

Formula

C₁₀₅H₁₆₀N₃₀O₂₆S₄

CAS No.

128315-56-0

Sequence Shortening

DFDMLRCMLGRVYRPCWQV (Disulfide bridge:Cys7-Cys16)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

MCH(human, mouse, rat)MCHR1 (GPR24)Melanin concentrating hormone receptor 1Inhibitorinhibitorinhibit

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MCH(human, mouse, rat)
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HY-P1205
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