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  5. Cyclosporin G

Cyclosporin G is an active metabolite that can be produced from Tolypocladium inflatum. Cyclosporin G has immunosuppressive activity. Cyclosporin G inhibits proliferation of A431 cells.

For research use only. We do not sell to patients.

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Cyclosporin G

Cyclosporin G Chemical Structure

CAS No. : 74436-00-3

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Cyclosporin G Related Antibodies

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Description

Cyclosporin G is an active metabolite that can be produced from Tolypocladium inflatum. Cyclosporin G has immunosuppressive activity. Cyclosporin G inhibits proliferation of A431 cells[1][2].

Molecular Weight

1216.64

Formula

C63H113N11O12
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (82.19 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8219 mL 4.1097 mL 8.2194 mL
5 mM 0.1644 mL 0.8219 mL 1.6439 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8219 mL 4.1097 mL 8.2194 mL 20.5484 mL
5 mM 0.1644 mL 0.8219 mL 1.6439 mL 4.1097 mL
10 mM 0.0822 mL 0.4110 mL 0.8219 mL 2.0548 mL
15 mM 0.0548 mL 0.2740 mL 0.5480 mL 1.3699 mL
20 mM 0.0411 mL 0.2055 mL 0.4110 mL 1.0274 mL
25 mM 0.0329 mL 0.1644 mL 0.3288 mL 0.8219 mL
30 mM 0.0274 mL 0.1370 mL 0.2740 mL 0.6849 mL
40 mM 0.0205 mL 0.1027 mL 0.2055 mL 0.5137 mL
50 mM 0.0164 mL 0.0822 mL 0.1644 mL 0.4110 mL
60 mM 0.0137 mL 0.0685 mL 0.1370 mL 0.3425 mL
80 mM 0.0103 mL 0.0514 mL 0.1027 mL 0.2569 mL
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Cyclosporin G Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclosporin G74436-00-3OthersA431Inhibitorinhibitorinhibit

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