Cyclosporin G
Based on 1 Customer Validation
Cyclosporin G is an active metabolite that can be produced from Tolypocladium inflatum. Cyclosporin G has immunosuppressive activity. Cyclosporin G inhibits proliferation of A431 cells.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 74436-00-3
- Formula: C63H113N11O12
- Molecular Weight:1216.64
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 74436-00-3
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Appearance Solid
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Molecular Weight 1216.64
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Formula C63H113N11O12
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (82.19 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Burdmann EA, et al. Experimental nephrotoxicity, hepatotoxicity and pharmacokinetics of cyclosporin G versus cyclosporin A. Kidney Int. 1994 Mar;45(3):684-91. [Content Brief]
[2]. Teofoli P, et al. Cyclosporin G inhibits proliferation of A431 cells in a dose- and time-dependent manner comparable to cyclosporin A. Skin Pharmacol. 1997;10(2):79-84. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8219 mL | 4.1097 mL | 8.2194 mL | 20.5484 mL |
| 5 mM | 0.1644 mL | 0.8219 mL | 1.6439 mL | 4.1097 mL | |
| 10 mM | 0.0822 mL | 0.4110 mL | 0.8219 mL | 2.0548 mL | |
| 15 mM | 0.0548 mL | 0.2740 mL | 0.5480 mL | 1.3699 mL | |
| 20 mM | 0.0411 mL | 0.2055 mL | 0.4110 mL | 1.0274 mL | |
| 25 mM | 0.0329 mL | 0.1644 mL | 0.3288 mL | 0.8219 mL | |
| 30 mM | 0.0274 mL | 0.1370 mL | 0.2740 mL | 0.6849 mL | |
| 40 mM | 0.0205 mL | 0.1027 mL | 0.2055 mL | 0.5137 mL | |
| 50 mM | 0.0164 mL | 0.0822 mL | 0.1644 mL | 0.4110 mL | |
| 60 mM | 0.0137 mL | 0.0685 mL | 0.1370 mL | 0.3425 mL | |
| 80 mM | 0.0103 mL | 0.0514 mL | 0.1027 mL | 0.2569 mL |
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