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Cat. No.: HY-129092

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8-(p-Sulfophenyl)theophylline

(Synonyms: 8-SPT; 8-pSPT)

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8-(p-Sulfophenyl)theophylline (8-SPT) (compound 2) is an adenosine A2B receptor antagonist, with a K_i of 1330 nM for A2B human recombinant.

For research use only. We do not sell to patients.

Purity: ≥98.0%
CAS No.: 80206-91-3
Formula: C₁₃H₁₂N₄O₅S
Molecular Weight:336.32

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

8-(p-Sulfophenyl)theophylline Chemical Structure

CAS No.: 80206-91-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

8-(p-Sulfophenyl)theophylline (8-SPT) (compound 2) is an adenosine A2B receptor antagonist, with a K_i of 1330 nM for A2B human recombinant^[1].

IC₅₀ & Target^[1]

hA_2B

1330 nM (Ki)

All Adenosine Receptor Isoforms :

Chemical Information

CAS No. 80206-91-3
Appearance Solid
Molecular Weight 336.32
Formula C₁₃H₁₂N₄O₅S
SMILES

O=C1C=2NC(=NC2N(C(=O)N1C)C)C=3C=CC(=CC3)S(=O)(=O)O
Synonyms

8-SPT; 8-pSPT
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yan L, et al. A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists. J Med Chem. 2006 Jul 13;49(14):4384-91. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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8-(p-​Sulfophenyl)​theophylline

All Adenosine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

8-(p-​Sulfophenyl)​theophylline Related Classifications

HY-129092 Related Classifications

8-(p-Sulfophenyl)theophylline

8-(p-Sulfophenyl)theophylline Related Classifications