CKS9
Based on 1 Customer Validation
CKS9 is an M cell-targeting polypeptide with the amino acid sequence CKSTHPLSC, forming a 9-mer peptide via cyclization through a disulfide bond between the two cysteine residues. CKS9 is obtained through phage display technology screening and has high affinity for M cells. CKS9 can promote chitosan nanoparticles to cross M cells and enter the follicle-associated epithelium (FAE) of intestinal Peyer's patches (PP). CKS9 can be used in studies related to swine dysentery and oral delivery.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.68%
- Formel: C39H64N12O13S2
- Molecular Weight:973.13
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Speicherung:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
CKS9 can be successfully grafted onto stearic acid esterified starch to form SES@CKS9-1 and SES@CKS9-2[1].
CKS9-modified SES exhibits stronger binding affinity to integrin α5β1 than unmodified SES. CKS9 mediates key hydrogen-bond interactions at the interface of the βI/β-propeller domain of integrin, suggesting that integrin α5β1 is a potential M cell receptor for CKS9[1].
CKS9 is conjugated with WSC via EDC/NHS, with a molar ratio of 6.37 mol%[2].
As the C-terminal component of a computationally designed multi-epitope oral vaccine against *Helicobacter pylori*, CKS9 targets intestinal epithelial microfold cells to enhance the intestinal barrier uptake of the vaccine[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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Appearance Solid
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Molecular Weight 973.13
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Formel C39H64N12O13S2
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Sequence
Cys-Lys-Ser-Thr-His-Pro-Leu-Ser-Cys (Disulfide bridge:Cys1-Cys9)
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Sequence Shortening
CKSTHPLSC (Disulfide bridge:Cys1-Cys9)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Reinheit & Dokumentation
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Data Sheet (262 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CKS9 Related Classifications
HY-P11422 Related Classifications
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