1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. Adenosine-2-carboxamide

Adenosine-2-carboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

Adenosine-2-carboxamide

Adenosine-2-carboxamide Chemical Structure

CAS No. : 70255-72-0

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Description

Adenosine-2-carboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

310.27

Formula

C11H14N6O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O)[C@H](N2C(N=C(C(N)=O)N=C3N)=C3N=C2)O[C@@H]1CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

1 M HCl : ≥ 100 mg/mL (322.30 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2230 mL 16.1150 mL 32.2300 mL
5 mM 0.6446 mL 3.2230 mL 6.4460 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
1 M HCl 1 mM 3.2230 mL 16.1150 mL 32.2300 mL 80.5750 mL
5 mM 0.6446 mL 3.2230 mL 6.4460 mL 16.1150 mL
10 mM 0.3223 mL 1.6115 mL 3.2230 mL 8.0575 mL
15 mM 0.2149 mL 1.0743 mL 2.1487 mL 5.3717 mL
20 mM 0.1611 mL 0.8057 mL 1.6115 mL 4.0287 mL
25 mM 0.1289 mL 0.6446 mL 1.2892 mL 3.2230 mL
30 mM 0.1074 mL 0.5372 mL 1.0743 mL 2.6858 mL
40 mM 0.0806 mL 0.4029 mL 0.8057 mL 2.0144 mL
50 mM 0.0645 mL 0.3223 mL 0.6446 mL 1.6115 mL
60 mM 0.0537 mL 0.2686 mL 0.5372 mL 1.3429 mL
80 mM 0.0403 mL 0.2014 mL 0.4029 mL 1.0072 mL
100 mM 0.0322 mL 0.1611 mL 0.3223 mL 0.8057 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Adenosine-2-carboxamide
Cat. No.:
HY-152318
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