2. Anti-infection
  3. HBV
  4. 2'-Deoxy-L-adenosine

2'-Deoxy-L-adenosine is an orally active synthon for modified oligodeoxyribonucleotides. 2'-Deoxy-L-adenosine is a potent, specific and selective inhibitor of the replication of hepatitis B virus (HBV) as well as the closely related duck and woodchuck hepatitis viruses (WHV).

For research use only. We do not sell to patients.

2'-Deoxy-L-adenosine Chemical Structure

2'-Deoxy-L-adenosine Chemical Structure

CAS No. : 14365-45-8

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2'-Deoxy-L-adenosine Related Antibodies

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Description

2'-Deoxy-L-adenosine is an orally active synthon for modified oligodeoxyribonucleotides. 2'-Deoxy-L-adenosine is a potent, specific and selective inhibitor of the replication of hepatitis B virus (HBV) as well as the closely related duck and woodchuck hepatitis viruses (WHV)[1].

In Vitro

2'-Deoxy-L-adenosine shows anti-hepadnavirus activity, withour affecting the replication of 15 other RNA and DNA viruses, neither nor inhibiting human DNA polymerases (α, β, and γ) or compromise mitochondrial function[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2'-Deoxy-L-adenosine Related Antibodies
In Vivo

2'-Deoxy-L-adenosine (p.o.; once daily) reduces viral load by as much as 108 genome equivalent/mL serum without drug-related toxicity in woodchuck efficacy model of chronic HBV infection[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

251.24

Formula

C10H13N5O3
CAS No.
SMILES

NC1=NC=NC2=C1N=CN2[C@@H]3C[C@@H](O)[C@H](CO)O3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2'-Deoxy-L-adenosine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2'-Deoxy-L-adenosine14365-45-8HBVHepatitis B virusoligodeoxyribonucleotidesviral enzymedeoxyadenosinehepatitis viruseshepatitis B virusWHVanti-hepadnavirus activitywoodchuck efficacy model of chronic HBV infectionInhibitorinhibitorinhibit

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