5-Fluorouridine 5'-phosphate
Based on 1 Customer Validation
5-Fluorouridine 5'-phosphate is an ODCase (orotidine-5′-monophosphate decarboxylase) inhibitor, with a Ki value of 98 µM for human ODCase and a Ki value of 645 µM for Methanobacterium ODCase. 5-Fluorouridine 5'-phosphate exhibits inhibitory activity against leukemia and lymphoma cell lines and can be used in cancer research .
For research use only. We do not sell to patients.
- Purity: 98.73%
- CAS No.: 796-66-7
- Formula: C9H12FN2O9P
- Molecular Weight:342.17
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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CAS No. 796-66-7
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Appearance Solid
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Molecular Weight 342.17
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Formula C9H12FN2O9P
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Color Off-white to light yellow
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SMILES
O=C(N1)N([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C=C(F)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
H2O : 100 mg/mL (292.25 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.9225 mL | 14.6126 mL | 29.2252 mL | 73.0631 mL |
| 5 mM | 0.5845 mL | 2.9225 mL | 5.8450 mL | 14.6126 mL | |
| 10 mM | 0.2923 mL | 1.4613 mL | 2.9225 mL | 7.3063 mL | |
| 15 mM | 0.1948 mL | 0.9742 mL | 1.9483 mL | 4.8709 mL | |
| 20 mM | 0.1461 mL | 0.7306 mL | 1.4613 mL | 3.6532 mL | |
| 25 mM | 0.1169 mL | 0.5845 mL | 1.1690 mL | 2.9225 mL | |
| 30 mM | 0.0974 mL | 0.4871 mL | 0.9742 mL | 2.4354 mL | |
| 40 mM | 0.0731 mL | 0.3653 mL | 0.7306 mL | 1.8266 mL | |
| 50 mM | 0.0585 mL | 0.2923 mL | 0.5845 mL | 1.4613 mL | |
| 60 mM | 0.0487 mL | 0.2435 mL | 0.4871 mL | 1.2177 mL | |
| 80 mM | 0.0365 mL | 0.1827 mL | 0.3653 mL | 0.9133 mL | |
| 100 mM | 0.0292 mL | 0.1461 mL | 0.2923 mL | 0.7306 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.