Phomopsin D
Phomopsin D, a mycotoxin, is a derivative of Phomopsin A (HY-N6793). Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis. Phomopsin A is a noncompetitive inhibitor of the binding of radiolabeled vincristine to tubulin.
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- CAS. Nr.: 175617-09-1
- Formel: C36H47ClN6O12
- Molecular Weight:791.24
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 175617-09-1
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Molecular Weight 791.24
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Formel C36H47ClN6O12
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SMILES
O=C(N[C@H]1C(C)=C)[C@@H](NC)[C@@H](O)C2=CC(Cl)=C(O)C(O[C@](C)(CC)[C@@H](C(N3[C@@](C(N/C(C(NC(CC(O)=O)C(O)=O)=O)=C(C)/CC)=O)([H])C=CC3)=O)NC1=O)=C2
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Structure Classification
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Initial Source
Rhizopus oligosporus
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Sogahata K, et al. Biosynthetic Studies of Phomopsins Unveil Posttranslational Installation of Dehydroamino Acids by UstYa Family Proteins. Angew Chem Int Ed Engl. 2021 Dec 1;60(49):25729-25734. [Content Brief]
[2]. Hamel E. Natural products which interact with tubulin in the vinca domain: maytansine, rhizoxin, phomopsin A, dolastatins 10 and 15 and halichondrin B. Pharmacol Ther. 1992;55(1):31-51. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Phomopsin D Related Classifications
HY-N16440 Related Classifications
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