Nitrobenzylthioinosine 5'-monophosphate
Nitrobenzylthioinosine 5'-monophosphate (NBMPR-P), a nucleoside analog, is a prodrug of the potent nucleoside transport inhibitor Nitro-benzylthioinosine (NBMPR) (HY-W010936). Nitrobenzylthioinosine 5'-monophosphate blocks nucleoside transport in vivo and prevents host toxicity in tumor-bearing mice administered with highdoses of Tubercidin (HY-100126).
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- CAS No.: 65199-10-2
- Formula: C17H18N5O9PS
- Molecular Weight:499.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 65199-10-2
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Molecular Weight 499.39
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Formula C17H18N5O9PS
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N(C=N2)C3=C2C(SCC4=CC=C([N+]([O-])=O)C=C4)=NC=N3
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Synonyms
NBMPR-P
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Patel DH, et al. Retroviral transfer of the hENT2 nucleoside transporter cDNA confers broad-spectrum antifolate resistance in murine bone marrow cells. Blood. 2000 Apr 1;95(7):2356-63. [Content Brief]
[2]. el Kouni MH, et al. Combination therapy of schistosomiasis by tubercidin and nitrobenzylthioinosine 5'-monophosphate. Proc Natl Acad Sci U S A. 1983 Nov;80(21):6667-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nitrobenzylthioinosine 5'-monophosphate Related Classifications
HY-177059 Related Classifications
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