DOTA-C1-FAP-2286
DOTA-C1-FAP-2286 is a cysteic acid-modified fibroblast activation protein (FAP)-targeting radioligand. DOTA-C1-FAP-2286 binds competitively to FAP with an IC50 of 127.64 nM. DOTA-C1-FAP-2286 is targeted accumulation in FAP-expressing cells and exhibits accelerated renal clearance. DOTA-C1-FAP-2286 can be used as a PET/CT tracer in cancer.
For research use only. We do not sell to patients.
- CAS No.: 3107530-08-2
- Formula: C73H109N15O26S5
- Molecular Weight:1773.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
DOTA-C1-FAP-2286 (10−11 to 10−5 M; 60 min) competitively binds to [177Lu]Lu-FAP-2286 in A549-FAP cells with an IC50 of 127.64 ± 23.40 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3107530-08-2
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Molecular Weight 1773.06
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Formula C73H109N15O26S5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DOTA-C1-FAP-2286 Related Classifications
HY-P11602 Related Classifications
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