DOTA-C1-FAP-2286
DOTA-C1-FAP-2286 is a cysteic acid-modified fibroblast activation protein (FAP)-targeting radioligand. DOTA-C1-FAP-2286 binds competitively to FAP with an IC50 of 127.64 nM. DOTA-C1-FAP-2286 is targeted accumulation in FAP-expressing cells and exhibits accelerated renal clearance. DOTA-C1-FAP-2286 can be used as a PET/CT tracer in cancer.
For research use only. We do not sell to patients.
- CAS No.: 3107530-08-2
- Formula: C73H109N15O26S5
- Molecular Weight:1773.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
DOTA-C1-FAP-2286 (10−11 to 10−5 M; 60 min) competitively binds to [177Lu]Lu-FAP-2286 in A549-FAP cells with an IC50 of 127.64 ± 23.40 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Chemical Information
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CAS No. 3107530-08-2
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Molecular Weight 1773.06
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Formula C73H109N15O26S5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DOTA-C1-FAP-2286 Related Classifications
HY-P11602 Related Classifications
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