Thiamine monophosphate chloride dihydrate

Name: Thiamine monophosphate chloride dihydrate
Brand: MedChemExpress
SKU: HY-128742
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Cat. No.: HY-128742 Pureza: 99.24%: Ficha de datos
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Thiamine monophosphate chloride dihydrate is a vitamin B1 (HY-A0100) metabolite and thiamine precursor. Thiamine monophosphate chloride dihydrate is absorbable in vivo and can be converted into thiamine. Thiamine monophosphate chloride dihydrate can be used as a food additive.

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Thiamine monophosphate chloride dihydrate Estructura química

No. CAS : 273724-21-3

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	En stock	Estimated Time of Arrival: December 31
Solid
500 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
5 g	Obtener un presupuesto
10 g	Obtener un presupuesto

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Based on 1 Customer Validation

Other Forms of Thiamine monophosphate chloride dihydrate:

Thiamine monophosphate chloride dihydrate (Standard) Obtener un presupuesto

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•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

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Human Endogenous Metabolite Microbial Metabolite

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Descripciòn

In Vivo

Thiamine monophosphate (240 mg thiamine equivalent/kg bw; i.p.; consecutive 28 days) chloride dihydrate exhibits toxicity in rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	healthy rats^[1]
Dosage:	240 mg thiamine equivalent/kg bw
Administration:	i.p.; daily; 28 days
Result:	Resulted in 15% mortality in rats, compared to 38% mortality with Thiamine.

Peso molecular

416.82

Fòrmula

C₁₂H₂₂ClN₄O₆PS

No. CAS

273724-21-3

Appearance

Solid

Color

White to off-white

SMILES

O=P(OCCC1=C(C)[N+](CC2=CN=C(C)N=C2N)=CS1)(O)O.[Cl-].[2H2O]

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O : 125 mg/mL (299.89 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3991 mL	11.9956 mL	23.9912 mL
5 mM	0.4798 mL	2.3991 mL	4.7982 mL
10 mM	0.2399 mL	1.1996 mL	2.3991 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (239.91 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 99.24%

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Ficha de datos (274 KB) SDS (393 KB)

COA (252 KB) HNMR (261 KB) RP-HPLC (205 KB) MS (76 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Aguilar F, et al. Benfotiamine, thiamine monophosphate chloride and thiamine pyrophosphate chloride, as sources of vitamin B1 added nutritional purposes to food supplements. EFSA JOURNAL, 2008, 864: 1-31.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.3991 mL	11.9956 mL	23.9912 mL	59.9779 mL
	5 mM	0.4798 mL	2.3991 mL	4.7982 mL	11.9956 mL
	10 mM	0.2399 mL	1.1996 mL	2.3991 mL	5.9978 mL
	15 mM	0.1599 mL	0.7997 mL	1.5994 mL	3.9985 mL
	20 mM	0.1200 mL	0.5998 mL	1.1996 mL	2.9989 mL
	25 mM	0.0960 mL	0.4798 mL	0.9596 mL	2.3991 mL
	30 mM	0.0800 mL	0.3999 mL	0.7997 mL	1.9993 mL
	40 mM	0.0600 mL	0.2999 mL	0.5998 mL	1.4994 mL
	50 mM	0.0480 mL	0.2399 mL	0.4798 mL	1.1996 mL
	60 mM	0.0400 mL	0.1999 mL	0.3999 mL	0.9996 mL
	80 mM	0.0300 mL	0.1499 mL	0.2999 mL	0.7497 mL
	100 mM	0.0240 mL	0.1200 mL	0.2399 mL	0.5998 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.