hA2AAR antagonist 1
hA2AAR antagonist 1 (compound 4a) is a highly selective hA2AAR antagonist with a Ki of 5 nM. hA2AAR antagonist 1 can be used in the study of immune-oncology.
For research use only. We do not sell to patients.
- CAS No.: 2842150-81-4
- Formula: C15H15N5O
- Molecular Weight:281.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | EC50 |
13.3 nM
Compound: 4a
|
Immuno-therapeutic activity in human PBMC cells assessed as restoration of NECA-inhibited IL-2 secretion by measuring recovery efficacy incubated for 24 hrs by ELISA relative to control
Immuno-therapeutic activity in human PBMC cells assessed as restoration of NECA-inhibited IL-2 secretion by measuring recovery efficacy incubated for 24 hrs by ELISA relative to control
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[PMID: 38845345] |
Chemical Information
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CAS No. 2842150-81-4
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Molecular Weight 281.31
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Formula C15H15N5O
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SMILES
NC1=NC(C2=CC=CO2)=NC3=C1N=C(N3)C#CCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hA2AAR antagonist 1 Related Classifications
HY-163701 Related Classifications
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