PDE10A-IN-5
PDE10A-IN-5 (Compound A30) is an inhibitor of phosphodiesterase 10A (PDE10A) with oral activity, and its IC50 value is 3.5 nM. PDE10A-IN-5 exerts the activity of inhibiting pulmonary vascular remodeling by inhibiting PDE10A and activating the cyclic adenosine monophosphate (cAMP)-associated signaling pathway, and can be used for research in the field of pulmonary arterial hypertension.
For research use only. We do not sell to patients.
- Formula: C29H34N6O3
- Molecular Weight:514.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PDE10A 3.5 nM (IC50) |
Chemical Information
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Molecular Weight 514.62
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Formula C29H34N6O3
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SMILES
O=C(C1=C(C2CN(C3=NC4=CC=CC=C4C(C(NCCN(CC)CC)=O)=C3)C2)N=C5C=CC=CN51)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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