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  2. Cyclic MKEY

Cyclic MKEY 

Cat. No.: HY-P1949
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Cyclic MKEY is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY also protects against stroke-induced brain injury in mice.

For research use only. We do not sell to patients.

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Cyclic MKEY Chemical Structure

Cyclic MKEY Chemical Structure

CAS No. : 934385-55-4

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Description

Cyclic MKEY is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY also protects against stroke-induced brain injury in mice[1][2].

IC50 & Target

CXCL4-CCL5 heterodimer formation[1]

Molecular Weight

2532.89

Formula

C₁₁₃H₁₇₄N₂₈O₃₄S₂

CAS No.

934385-55-4

Sequence

{Cys}{Lys}{Glu}{Tyr}{Phe}{Tyr}{Thr}{Ser}{Ser}{Lys}{Ser}{Ser}{Asn}{Leu}{Ala}{Val}{Val}{Phe}{Val}{Thr]

Sequence Shortening

CKEYFYTSSKSSNLAVVFVTRC

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Cyclic MKEY
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HY-P1949
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