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CCP peptide 

Cat. No.: HY-P2171
Handling Instructions

CCP peptide is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

CCP peptide Chemical Structure

CCP peptide Chemical Structure

CAS No. : 277748-59-1

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Description

CCP peptide is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA)[1][2].

In Vivo

CCP peptide is used as a new antigenic substrate in anti-CCP ELISA to detect anti-citrullinated protein antibodies (ACPAs). The anti-CCP ELISA is extremely specific (98%), with a reasonable sensitivity (68%). The anti-CCP ELISA is very useful for diagnostic and therapeutic strategies in rheumatoid arthritis (RA)[3].

Molecular Weight

2341.47

Formula

C₈₇H₁₄₅N₄₁O₃₂S₂

CAS No.

277748-59-1

Sequence

{His}{Gln}{Cys}{His}{Gln}{Glu}{Ser}{Thr}{Cit}{Gly}{Arg}{Ser}{Arg}{Gly}{Arg}{Cys}{Gly}{Arg}{Ser}{Gly}{Ser}(Disulfide bridge: Cys3-Cys16)

Sequence Shortening

HQCHQEST-{Cit}-GRSRGRCGRSGS(Disulfide bridge: Cys3-Cys16)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CCP peptideOthersRheumatoidarthritissyntheticcycliccitrullinatedanti-CCPantibodiesserologicallyInhibitorinhibitorinhibit

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CCP peptide
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HY-P2171
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