1. Immunology/Inflammation
  2. STING
  3. IACS-8803 disodium

IACS-8803 disodium 

Cat. No.: HY-130115A Purity: 99.97%
Handling Instructions

IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy.

For research use only. We do not sell to patients.

IACS-8803 disodium Chemical Structure

IACS-8803 disodium Chemical Structure

CAS No. : 2243079-36-7

Size Price Stock Quantity
1 mg USD 480 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1].

In Vivo

IACS-8803 (10 µg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

738.51

Formula

C₂₀H₂₃FN₁₀Na₂O₉P₂S₂

CAS No.

2243079-36-7

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 56.67 mg/mL (76.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3541 mL 6.7704 mL 13.5408 mL
5 mM 0.2708 mL 1.3541 mL 2.7082 mL
10 mM 0.1354 mL 0.6770 mL 1.3541 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

IACS-8803 disodiumSTINGStimulator of Interferon GenesTMEM173MITAERISMPYSAntitumorintra-tumoralcyclicdinucleotideInhibitorinhibitorinhibit

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Product Name:
IACS-8803 disodium
Cat. No.:
HY-130115A
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