1. Immunology/Inflammation
  2. STING
  3. IACS-8803

IACS-8803 

Cat. No.: HY-130115
Handling Instructions

IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy.

For research use only. We do not sell to patients.

IACS-8803 Chemical Structure

IACS-8803 Chemical Structure

CAS No. : 2095690-70-1

Size Price Stock Quantity
1 mg USD 480 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
25 mg USD 3900 In-stock
Estimated Time of Arrival: December 31
50 mg USD 6200 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy[1].

IC50 & Target

STING[1]

In Vivo

IACS-8803 shows a superior systemic anti-tumor response in the B16 murine model of melanoma[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

692.53

Formula

C₂₀H₂₃FN₁₀O₉P₂S₂

CAS No.

2095690-70-1

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 15 mg/mL (21.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4440 mL 7.2199 mL 14.4398 mL
5 mM 0.2888 mL 1.4440 mL 2.8880 mL
10 mM 0.1444 mL 0.7220 mL 1.4440 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

IACS-8803IACS8803IACS 8803STINGStimulator of Interferon GenesTMEM173MITAERISMPYSantitumorefficacyB16murinemelanomaInhibitorinhibitorinhibit

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IACS-8803
Cat. No.:
HY-130115
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