(R,R)-Cyclo(Pro-Val)

Cat. No.: HY-N11615A Purity: 99.51%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

(R,R)-Cyclo(Pro-Val) is a trans (D-L) diastereoisomer of valyl-prolyl diketopiperazine (cyclic dipeptide).

For research use only. We do not sell to patients.

(R,R)-Cyclo(Pro-Val) Chemical Structure

CAS No. : 22155-59-5

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of (R,R)-Cyclo(Pro-Val):

Cyclo(Pro-Val) In-stock

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

(R,R)-Cyclo(Pro-Val) is a trans (D-L) diastereoisomer of valyl-prolyl diketopiperazine (cyclic dipeptide)^[1].

In Vitro

(R,R)-Cyclo (Pro-Val) is the trans (D-L) diastereomer of valyl-prolyl diketopiperazine (cyclodipeptide)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

196.25

Formula

C₁₀H₁₆N₂O₂

CAS No.

22155-59-5

Appearance

Solid

Color

White to off-white

SMILES

O=C1N2[C@@](C(=O)N[C@@H]1C(C)C)(CCC2)[H]

Structure Classification

Initial Source

Microorganisms

Aspergillus austwickii

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (254.78 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.0955 mL	25.4777 mL	50.9554 mL
5 mM	1.0191 mL	5.0955 mL	10.1911 mL
10 mM	0.5096 mL	2.5478 mL	5.0955 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.51%

Select Batch:

Data Sheet (273 KB) SDS (254 KB)

COA (252 KB) HNMR (158 KB) RP-HPLC (109 KB) Elemental Analysis Report (112 KB)

Handling Instructions (2659 KB)

References

[1]. Mauger AB. Gas-liquid chromatography of diketopiperazines. J Chromatogr. 1968 Oct 8;37(2):315-7.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.0955 mL	25.4777 mL	50.9554 mL	127.3885 mL
	5 mM	1.0191 mL	5.0955 mL	10.1911 mL	25.4777 mL
	10 mM	0.5096 mL	2.5478 mL	5.0955 mL	12.7389 mL
	15 mM	0.3397 mL	1.6985 mL	3.3970 mL	8.4926 mL
	20 mM	0.2548 mL	1.2739 mL	2.5478 mL	6.3694 mL
	25 mM	0.2038 mL	1.0191 mL	2.0382 mL	5.0955 mL
	30 mM	0.1699 mL	0.8493 mL	1.6985 mL	4.2463 mL
	40 mM	0.1274 mL	0.6369 mL	1.2739 mL	3.1847 mL
	50 mM	0.1019 mL	0.5096 mL	1.0191 mL	2.5478 mL
	60 mM	0.0849 mL	0.4246 mL	0.8493 mL	2.1231 mL
	80 mM	0.0637 mL	0.3185 mL	0.6369 mL	1.5924 mL
	100 mM	0.0510 mL	0.2548 mL	0.5096 mL	1.2739 mL

(R,R)-Cyclo(Pro-Val) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R,R)-Cyclo(Pro-Val)22155-59-5Drug DerivativeDrug derivativevalyl-prolyl diketopiperazinecyclic dipeptideInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Requested Quantity *

Applicant Name *

Salutation

Email Address *

Phone Number *

Department

Organization Name *

City

State

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *