BODIPY 630/650X

Name: BODIPY 630/650X
Brand: MedChemExpress
SKU: HY-110213
Rating: 4.5 (1 reviews)

Cat. No.: HY-110213 Purity: 96.20%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

BODIPY 630/650X is a fluorescent conjugate of the adenosine receptor ligand N-ethylcarboxamido-adenosine (NECA). BODIPY 630/650X displays excitation/emission maxima of 630/650 nm, respectively.

For research use only. We do not sell to patients.

BODIPY 630/650X Chemical Structure

CAS No. : 380367-48-6

Size	Price	Stock	Quantity
1 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Description

BODIPY 630/650X is a fluorescent conjugate of the adenosine receptor ligand N-ethylcarboxamido-adenosine (NECA). BODIPY 630/650X displays excitation/emission maxima of 630/650 nm, respectively^[1].

Molecular Weight

660.50

Formula

C₃₃H₃₁BF₂N₄O₆S

CAS No.

380367-48-6

Appearance

Solid

Color

Dark purple to black

Emission (Em)

650

Excitation (Ex)

630

SMILES

O=C(CCCCCNC(COC1=CC=C(/C=C/C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N]4[B+3]([F-])([N-]23)[F-])C=C1)=O)ON6C(CCC6=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (75.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5140 mL	7.5700 mL	15.1400 mL
5 mM	0.3028 mL	1.5140 mL	3.0280 mL
10 mM	0.1514 mL	0.7570 mL	1.5140 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.25 mg/mL (1.89 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 96.20%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (253 KB) RP-HPLC (204 KB)

Handling Instructions (2659 KB)

References

[1]. Dale C L , et al. New potent, short-linker BODIPY-630/650™ labelled fluorescent adenosine receptor agonists. Med.chem.commun, 2012, 3.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5140 mL	7.5700 mL	15.1400 mL	37.8501 mL
	5 mM	0.3028 mL	1.5140 mL	3.0280 mL	7.5700 mL
	10 mM	0.1514 mL	0.7570 mL	1.5140 mL	3.7850 mL
	15 mM	0.1009 mL	0.5047 mL	1.0093 mL	2.5233 mL
	20 mM	0.0757 mL	0.3785 mL	0.7570 mL	1.8925 mL
	25 mM	0.0606 mL	0.3028 mL	0.6056 mL	1.5140 mL
	30 mM	0.0505 mL	0.2523 mL	0.5047 mL	1.2617 mL
	40 mM	0.0379 mL	0.1893 mL	0.3785 mL	0.9463 mL
	50 mM	0.0303 mL	0.1514 mL	0.3028 mL	0.7570 mL
	60 mM	0.0252 mL	0.1262 mL	0.2523 mL	0.6308 mL

BODIPY 630/650X Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BODIPY 630/650X380367-48-6Fluorescent DyeNECAadenosine receptorInhibitorinhibitorinhibit

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Complete Stock Solution Preparation Table

BODIPY 630/650X Related Classifications

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