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Cat. No.: HY-175395

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Onychocin B

Onychocin B is a cyclic tetrapeptide isolated from Onychocola sclerotica. Onychocin B is a calcium channel blocker with an IC₅₀ of 7.1 μM for Cav1.2.

For research use only. We do not sell to patients.

Formula: C₃₁H₄₂N₄O₄
Molecular Weight:534.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Onychocin B Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Onychocin B is a cyclic tetrapeptide isolated from Onychocola sclerotica. Onychocin B is a calcium channel blocker with an IC₅₀ of 7.1 μM for Cav1.2^[1].

IC₅₀ & Target

Ca_v1.2

7.1 μM (IC₅₀)

All Calcium Channel Isoforms :

Chemical Information

Molecular Weight 534.69
Formula C₃₁H₄₂N₄O₄
SMILES

O=C([C@H]([C@@H](C)CC)NC([C@H](CC1=CC=CC=C1)N(C)C([C@H](C(C)C)N2)=O)=O)N(C)[C@H](CC3=CC=CC=C3)C2=O
Structure Classification
- Antibiotics
- Macrolide Antibiotics
Initial Source
- Microorganisms
Onychocola sclerotica
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pérez-Victoria I, Martín J, et al. Isolation and structural elucidation of cyclic tetrapeptides from Onychocola sclerotica. J Nat Prod. 2012 Jun 22;75(6):1210-4. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References