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Cat. No.: HY-101980R

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Imaradenant (Standard)

(Synonyms: HTL1071 (Standard); AZD4635 (Standard))

Imaradenant (Standard) is the analytical standard of Imaradenant (HY-101980). This product is intended for research and analytical applications. AZD4635 (HTL1071) is a potent, selective and orally active adenosine A2A receptor (A2AR) antagonist. AZD4635 binds to human A2AR with a K_i of 1.7 nM and shows >30-fold selectivity over other adenosine receptors.

For research use only. We do not sell to patients.

CAS No.: 1321514-06-0
Formula: C₁₅H₁₁ClFN₅
Molecular Weight:315.73

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Imaradenant (Standard) Chemical Structure

CAS No.: 1321514-06-0

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Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1321514-06-0
Molecular Weight 315.73
Formula C₁₅H₁₁ClFN₅
SMILES

NC1=NC(C2=CC=C(F)C=C2)=C(C3=CC(Cl)=NC(C)=C3)N=N1
Synonyms

HTL1071 (Standard); AZD4635 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Alexandra Borodovsky, et al. Abstract 5580: Preclinical pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression. AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5580.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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