1. GPCR/G Protein
  2. Adenosine Receptor
  3. AZD4635

AZD4635 (Synonyms: HTL1071)

Cat. No.: HY-101980 Purity: 99.79%
Handling Instructions

AZD4635 is a novel adenosine 2A receptor (A2AR) inhibitor with a Ki of 1.7 nM.

For research use only. We do not sell to patients.

AZD4635 Chemical Structure

AZD4635 Chemical Structure

CAS No. : 1321514-06-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 132 In-stock
Estimated Time of Arrival: December 31
5 mg USD 120 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
50 mg USD 420 In-stock
Estimated Time of Arrival: December 31
100 mg USD 588 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

AZD4635 is a novel adenosine 2A receptor (A2AR) inhibitor with a Ki of 1.7 nM.

IC50 & Target

Ki: 1.7 nM (A2AR)

Clinical Trial
Molecular Weight

315.73

Formula

C₁₅H₁₁ClFN₅

CAS No.

1321514-06-0

SMILES

NC1=NC(C2=CC=C(F)C=C2)=C(C3=CC(Cl)=NC(C)=C3)N=N1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 83.3 mg/mL (263.83 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1673 mL 15.8363 mL 31.6726 mL
5 mM 0.6335 mL 3.1673 mL 6.3345 mL
10 mM 0.3167 mL 1.5836 mL 3.1673 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (6.59 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (6.59 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.79%

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
AZD4635
Cat. No.:
HY-101980
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