4-Desmethyl Istradefylline
4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 160434-48-0
- Formula: C19H22N4O4
- Molecular Weight:370.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
>10000 nM
Compound: 38
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Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 60 mins
Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 60 mins
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[PMID: 23602401] |
Chemical Information
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CAS No. 160434-48-0
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Molecular Weight 370.40
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Formula C19H22N4O4
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SMILES
O=C(N1CC)N(CC)C2=C(N(C)C(/C=C/C3=CC=C(O)C(OC)=C3)=N2)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Desmethyl Istradefylline Related Classifications
HY-135387 Related Classifications
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