160434-48-0
Chemical Structure
4-Desmethyl Istradefylline
- CAS No.: 160434-48-0
- Formula:C19H22N4O4
- Molecular Weight:370.40
IUPAC Name: (E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-3,7-dihydro-1H-purine-2,6-dione
InChIKey: OHGCYFOMTIEDMR-CSKARUKUSA-N
SMILES: O=C(N1CC)N(CC)C2=C(N(C)C(/C=C/C3=CC=C(O)C(OC)=C3)=N2)C1=O
Biological Activity: 4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease[1].
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4-Desmethyl Istradefylline | 4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease. | |||||||||||||||||||||
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Keywords