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Cat. No.: HY-137016

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8-Pcpt-cGMP

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

8-Pcpt-cGMP is an agonist for cyclic nucleotide-gated (CNG) channel with an EC₅₀ of 0.5 μM. 8-Pcpt-cGMP exhibits good membrane permeability. 8-Pcpt-cGMP can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction.

For research use only. We do not sell to patients.

CAS No.: 54364-02-2
Formula: C₁₆H₁₅ClN₅O₇PS
Molecular Weight:487.81

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

8-Pcpt-cGMP Chemical Structure

CAS No.: 54364-02-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 54364-02-2
Molecular Weight 487.81
Formula C₁₆H₁₅ClN₅O₇PS
SMILES

O[C@H]1[C@](O[C@@](CO2)([H])[C@@]1([H])O[P]2(O)=O)([H])N3C(NC(N)=NC4=O)=C4N=C3SC(C=C5)=CC=C5Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Sci Rep

NADPH oxidase 2 inhibitor GSK2795039 exerts antiplatelet and antithrombotic activity. [Abstract]

2025 Oct 16;15(1):36270. PMID: 41102391

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wei JY, et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998 Feb;10(1):53-64. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
Publications (1)
Purity & Documentation
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8-Pcpt-cGMP

Publications Citing Use of MedChemExpress (MCE) 8-Pcpt-cGMP