2. Peptides
  3. Cyclosporin B

Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cyclosporin B Chemical Structure

Cyclosporin B Chemical Structure

CAS No. : 63775-95-1

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1 mg USD 100 In-stock
5 mg USD 235 In-stock
10 mg USD 380 In-stock
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Based on 1 publication(s) in Google Scholar

Cyclosporin B Related Antibodies

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Description

Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation[1].

Molecular Weight

1188.58

Formula

C61H109N11O12
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (84.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8413 mL 4.2067 mL 8.4134 mL
5 mM 0.1683 mL 0.8413 mL 1.6827 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8413 mL 4.2067 mL 8.4134 mL 21.0335 mL
5 mM 0.1683 mL 0.8413 mL 1.6827 mL 4.2067 mL
10 mM 0.0841 mL 0.4207 mL 0.8413 mL 2.1034 mL
15 mM 0.0561 mL 0.2804 mL 0.5609 mL 1.4022 mL
20 mM 0.0421 mL 0.2103 mL 0.4207 mL 1.0517 mL
25 mM 0.0337 mL 0.1683 mL 0.3365 mL 0.8413 mL
30 mM 0.0280 mL 0.1402 mL 0.2804 mL 0.7011 mL
40 mM 0.0210 mL 0.1052 mL 0.2103 mL 0.5258 mL
50 mM 0.0168 mL 0.0841 mL 0.1683 mL 0.4207 mL
60 mM 0.0140 mL 0.0701 mL 0.1402 mL 0.3506 mL
80 mM 0.0105 mL 0.0526 mL 0.1052 mL 0.2629 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclosporin B63775-95-1OthersInhibitorinhibitorinhibit

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Cyclosporin B
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