1. Neuronal Signaling
  2. Beta-secretase
  3. BACE1-IN-8

BACE1-IN-8 

Cat. No.: HY-144739
Handling Instructions

BACE1-IN-8 (compound 70b) is a potent BACE1 (β-site APP cleaving enzyme 1) inhibitor, with an IC50 of 3.9 µM.

For research use only. We do not sell to patients.

BACE1-IN-8 Chemical Structure

BACE1-IN-8 Chemical Structure

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Description

BACE1-IN-8 (compound 70b) is a potent BACE1 (β-site APP cleaving enzyme 1) inhibitor, with an IC50 of 3.9 µM[1].

IC50 & Target

IC50: 3.9 µM (rBACE1)[1]

Molecular Weight

575.70

Formula

C29H45N5O7

SMILES

CCC[[email protected]@H]1NC([[email protected]@H](NC([[email protected]@H](N)CCC(O)=O)=O)C(OC/C=C\C[[email protected]@H]([[email protected]](O)CNC2=CC=C(C)C=C2)NC1=O)(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Product Name:
BACE1-IN-8
Cat. No.:
HY-144739
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