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Cat. No.: HY-120941

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LASSBio-1359

LASSBio-1359 is an adenosine A2A receptor agonist with vasodilatory and anti-inflammatory activities.

For research use only. We do not sell to patients.

CAS No.: 1396397-19-5
Formula: C₁₇H₁₈N₂O₃
Molecular Weight:298.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

LASSBio-1359 Chemical Structure

CAS No.: 1396397-19-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

LASSBio-1359 is an adenosine A2A receptor agonist with vasodilatory and anti-inflammatory activities^[1].

All Adenosine Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
PBMC	EC₅₀	1.75 μM Compound: 8a	Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha production after 24 hrs by ELISA Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha production after 24 hrs by ELISA	[PMID: 22891752]

Chemical Information

CAS No. 1396397-19-5
Molecular Weight 298.34
Formula C₁₇H₁₈N₂O₃
SMILES

O=C(C1=CC=CC=C1)N(/N=C/C2=CC=C(C(OC)=C2)OC)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Alencar AK, et al. Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline-induced pulmonary hypertension in rats. Br J Pharmacol. 2013 Jul;169(5):953-62. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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