N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite
Based on 1 Customer Validation
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
For research use only. We do not sell to patients.
- Purity : 98.04%
- CAS No.: 179479-02-8
- Formula: C48H54N7O8P
- Molecular Weight:887.96
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 179479-02-8
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Appearance Solid
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Molecular Weight 887.96
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Formula C48H54N7O8P
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Color White to off-white
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SMILES
CC(C)N(C(C)C)P(O[C@@H]1[C@H](OC)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N(C=N5)C6=C5C(NC(C7=CC=CC=C7)=O)=NC=N6)OCCC#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (112.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (278 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1262 mL | 5.6309 mL | 11.2618 mL | 28.1544 mL |
| 5 mM | 0.2252 mL | 1.1262 mL | 2.2524 mL | 5.6309 mL | |
| 10 mM | 0.1126 mL | 0.5631 mL | 1.1262 mL | 2.8154 mL | |
| 15 mM | 0.0751 mL | 0.3754 mL | 0.7508 mL | 1.8770 mL | |
| 20 mM | 0.0563 mL | 0.2815 mL | 0.5631 mL | 1.4077 mL | |
| 25 mM | 0.0450 mL | 0.2252 mL | 0.4505 mL | 1.1262 mL | |
| 30 mM | 0.0375 mL | 0.1877 mL | 0.3754 mL | 0.9385 mL | |
| 40 mM | 0.0282 mL | 0.1408 mL | 0.2815 mL | 0.7039 mL | |
| 50 mM | 0.0225 mL | 0.1126 mL | 0.2252 mL | 0.5631 mL | |
| 60 mM | 0.0188 mL | 0.0938 mL | 0.1877 mL | 0.4692 mL | |
| 80 mM | 0.0141 mL | 0.0704 mL | 0.1408 mL | 0.3519 mL | |
| 100 mM | 0.0113 mL | 0.0563 mL | 0.1126 mL | 0.2815 mL |
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite Related Classifications
HY-45281 Related Classifications
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