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Cat. No.: HY-P11576

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Cyclic αvβ6

Cyclic αvβ6 (Compound c(FRGDLAFp(NMe)K)) is a αvβ6-integrin-specific cyclic nonapeptide. Cyclic αvβ6 can be coupled with ⁶⁸Ga-labeled monomeric triazacyclononane-triphosphinate (TRAP). Cyclic αvβ6 can be used in PET imaging studies for cancers including head and neck cancer and pancreatic cancer.

For research use only. We do not sell to patients.

CAS No.: 2089299-82-9
Formula: C₅₁H₇₅N₁₃O₁₁
Molecular Weight:1046.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cyclic αvβ6 Chemical Structure

CAS No.: 2089299-82-9

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

αvβ6

All Integrin Isoforms :

All Radionuclide-Drug Conjugates (RDCs) Isoforms :

Chemical Information

CAS No. 2089299-82-9
Molecular Weight 1046.22
Formula C₅₁H₇₅N₁₃O₁₁
Sequence

c(Phe-Arg-Gly-Asp-Leu-Ala-Phe-DPro(NMe)-Lys)
Sequence Shortening

c(FRGDLAF-DPro(NMe)-K)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Quigley NG, et al. PET/CT imaging of head-and-neck and pancreatic cancer in humans by targeting the "Cancer Integrin" αvβ6 with Ga-68-Trivehexin. Eur J Nucl Med Mol Imaging. 2022 Mar;49(4):1136-1147. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Cyclic αvβ6

All Integrin Isoforms

All Radionuclide-Drug Conjugates (RDCs) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Cyclic αvβ6 Related Classifications

HY-P11576 Related Classifications