4,4'-(Cyclohexylidenemethylene)diphenol
4,4'-(Cyclohexylidenemethylene)diphenol (Compound 2) is a symmetric cyclic nonsteroidal estrogen. 4,4'-(Cyclohexylidenemethylene)diphenol has high binding affinity for estrogen receptors ERα and ERβ.
For research use only. We do not sell to patients.
- CAS No.: 5189-40-2
- Formula: C19H20O2
- Molecular Weight:280.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ERα |
ERβ |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | EC50 |
4.5 nM
Compound: DAC
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Effective dose for [3H]- estradiol against proliferation of MCF-7 cells
Effective dose for [3H]- estradiol against proliferation of MCF-7 cells
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[PMID: 2769681] |
| MCF7S | EC50 |
4.51 nM
Compound: 28
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Agonist activity against MCF-7 cell proliferation
Agonist activity against MCF-7 cell proliferation
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[PMID: 1738150] |
Chemical Information
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CAS No. 5189-40-2
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Molecular Weight 280.36
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Formula C19H20O2
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SMILES
OC1=CC=C(/C(C2=CC=C(C=C2)O)=C3CCCCC\3)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4,4'-(Cyclohexylidenemethylene)diphenol Related Classifications
HY-W615671 Related Classifications
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