Cyclo(GRGDSPA)
Cyclo(GRGDSPA) is a cyclic RGD peptide targeting αvβ3 integrin. Cyclo(GRGDSPA) reduces the formation of colonies in mice injected with B16-FE7 melanoma cells. Cyclo(GRGDSPA) can be used for melanoma research.
For research use only. We do not sell to patients.
- CAS No.: 128857-77-2
- Formula: C25H40N10O10
- Molecular Weight:640.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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αvβ3 |
Chemical Information
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CAS No. 128857-77-2
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Molecular Weight 640.65
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Formula C25H40N10O10
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Sequence
cyclo(Gly-Arg-Gly-Asp-Ser-Pro-Ala)
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Sequence Shortening
cyclo(GRGDSPA)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hazenbiller O, et al. Reduction of pluripotent gene expression in murine embryonic stem cells exposed to mechanical loading or Cyclo RGD peptide. BMC Cell Biol. 2017 Nov 14;18(1):32. [Content Brief]
[2]. Kumagai H, et al. Effect of cyclic RGD peptide on cell adhesion and tumor metastasis. Biochem Biophys Res Commun. 1991 May 31;177(1):74-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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