I942
Based on 1 Customer Validation
I942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases.
For research use only. We do not sell to patients.
- Purity: 99.47%
- CAS No.: 868145-09-9
- Formula: C20H19NO4S
- Molecular Weight:369.43
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
EPAC1[1]
Chemical Information
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CAS No. 868145-09-9
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Appearance Solid
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Molecular Weight 369.43
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Formula C20H19NO4S
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Color White to off-white
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SMILES
O=C(NS(=O)(C1=CC=C(C)C=C1C)=O)COC2=CC=C3C=CC=CC3=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (676.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7069 mL | 13.5344 mL | 27.0687 mL | 67.6718 mL |
| 5 mM | 0.5414 mL | 2.7069 mL | 5.4137 mL | 13.5344 mL | |
| 10 mM | 0.2707 mL | 1.3534 mL | 2.7069 mL | 6.7672 mL | |
| 15 mM | 0.1805 mL | 0.9023 mL | 1.8046 mL | 4.5115 mL | |
| 20 mM | 0.1353 mL | 0.6767 mL | 1.3534 mL | 3.3836 mL | |
| 25 mM | 0.1083 mL | 0.5414 mL | 1.0827 mL | 2.7069 mL | |
| 30 mM | 0.0902 mL | 0.4511 mL | 0.9023 mL | 2.2557 mL | |
| 40 mM | 0.0677 mL | 0.3384 mL | 0.6767 mL | 1.6918 mL | |
| 50 mM | 0.0541 mL | 0.2707 mL | 0.5414 mL | 1.3534 mL | |
| 60 mM | 0.0451 mL | 0.2256 mL | 0.4511 mL | 1.1279 mL | |
| 80 mM | 0.0338 mL | 0.1692 mL | 0.3384 mL | 0.8459 mL | |
| 100 mM | 0.0271 mL | 0.1353 mL | 0.2707 mL | 0.6767 mL |