1. Peptides
  2. Retrocyclin-1

Retrocyclin-1 is a kind of Theta-defensin. Retrocyclin-1 recognizes and binds to carbohydrate-containing surface molecules, to protect cells from HIV-1 infection. Retrocyclin-1 exhibits high affinity to fetuin, gp120 (Kd=35.4 nM), CD4 (Kd=31 nM), and galactosylceramide (Kd=24.1 nM).

For research use only. We do not sell to patients.

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Retrocyclin-1 Chemical Structure

Retrocyclin-1 Chemical Structure

CAS No. : 724760-19-4

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Description

Retrocyclin-1 is a kind of Theta-defensin. Retrocyclin-1 recognizes and binds to carbohydrate-containing surface molecules, to protect cells from HIV-1 infection. Retrocyclin-1 exhibits high affinity to fetuin, gp120 (Kd=35.4 nM), CD4 (Kd=31 nM), and galactosylceramide (Kd=24.1 nM)[1].

Molecular Weight

1918.39

Formula

C74H128N30O18S6

CAS No.
Sequence

Cyclo(-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg) (Disulfide bridge:Cys2-Cys11;Cys4-Cys9;Cys13-Cys18)

Sequence Shortening

RCICGRGICRCICGRGIC (Disulfide bridge:Cys2-Cys11;Cys4-Cys9;Cys13-Cys18)

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Retrocyclin-1
Cat. No.:
HY-P4902
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