724760-19-4
Chemical Structure
Retrocyclin-1
- CAS No.: 724760-19-4
- Formula:C74H128N30O18S6
- Molecular Weight:1918.39
InChIKey: HKPMSXLQWRKULW-QYJCGYSGSA-N
SMILES: NC(NCCC[C@H](NC(CNC([C@]([H])(CSSC1)NC([C@@]([C@H](CC)C)([H])NC([C@@](CSSC[C@](NC2=O)(C(N[C@@]([H])([C@H](CC)C)C(N[C@@]3([H])CSSC[C@@](NC([C@]([C@H](CC)C)(NC(CNC([C@@H](NC(CNC3=O)=O)CCCNC(N)=N)=O)=O)[H])=O)([H])C4=O)=O)=O)[H])([H])NC([C@H](CCCNC(N)=N)N4)=O)=O)=O)=O)=O)C(NCC(N[C@]([C@H](CC)C)([H])C(N[C@]1([H])C(N[C@H]2CCCNC(N)=N)=O)=O)=O)=O)=N
Biological Activity: Retrocyclin-1 is a kind of Theta-defensin. Retrocyclin-1 recognizes and binds to carbohydrate-containing surface molecules, to protect cells from HIV-1 infection. Retrocyclin-1 exhibits high affinity to fetuin, gp120 (Kd=35.4 nM), CD4 (Kd=31 nM), and galactosylceramide (Kd=24.1 nM)[1].
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Retrocyclin-1 | Retrocyclin-1 is a kind of Theta-defensin. Retrocyclin-1 recognizes and binds to carbohydrate-containing surface molecules, to protect cells from HIV-1 infection. Retrocyclin-1 exhibits high affinity to fetuin, gp120 (Kd=35.4 nM), CD4 (Kd=31 nM), and galactosylceramide (Kd=24.1 nM). | |||||||||||||||||||||
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