PD-143188
PD-143188 (CI 1007) is a selective agonist targeting dopamine (DA) receptors, with Ki values of 25.5 nM and 16.6 nM for human D2 and D3 receptors, respectively and lower affinity for D4.2 receptors (Ki=90.9 nM). PD-143188 inhibits DA release, synthesis and metabolism, while reducing cellular cyclic AMP levels, exerting antipsychotic activity. PD-143188 is promising for research of psychopharmacology.
For research use only. We do not sell to patients.
- CAS No.: 150013-70-0
- Formula: C24H27N
- Molecular Weight:329.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Dopamine Receptor Isoforms
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Biological Activity
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D2 Receptor 25.5 nM (Ki) |
D3 Receptor 16.6 nM (Ki) |
hD4.2 Receptor 90.9 nM (Ki) |
Chemical Information
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CAS No. 150013-70-0
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Molecular Weight 329.48
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Formula C24H27N
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SMILES
C1(C2=CC=CC=C2)=CCN(C[C@H]3CC(C4=CC=CC=C4)=CCC3)CC1
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Synonyms
CI 1007
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PD-143188 Related Classifications
HY-19186 Related Classifications
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