KIO-301 chloride
KIO-301 chloride is an azobenzene photoswitch compound that can block voltage-gated ion channels, including hyperpolarisation-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium channels during exposure to visible light.
For research use only. We do not sell to patients.
- CAS No.: 1643463-59-5
- Formula: C29H38ClN5O
- Molecular Weight:508.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
KIO-301 chloride is taken up selectively by viable retinal ganglion cells (RGCs) downstream of degenerated photoreceptors, rendering RGCs photoresponsive[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1643463-59-5
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Molecular Weight 508.10
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Formula C29H38ClN5O
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SMILES
O=C(C[N+](CC)(CC)CC)NC(C=C1)=CC=C1/N=N/C2=CC=C(N(CC3=CC=CC=C3)CC)C=C2.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KIO-301 chloride Related Classifications
HY-161092 Related Classifications
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