PF-05139962
PF-05139962 is a cyclic sulfone mTOR kinase inhibitor. PF-05139962 exhibits potent mTOR (Ki = 5 nM, pS473 IC50 = 48 nM, pS6 IC50 = 6 nM) inhibitory activity and high selectivity.
For research use only. We do not sell to patients.
- CAS No.: 1393712-18-9
- Formula: C21H27N5O4S
- Molecular Weight:445.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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mTOR 5 nM (Ki) |
Chemical Information
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CAS No. 1393712-18-9
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Molecular Weight 445.54
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Formula C21H27N5O4S
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SMILES
O=C(NCC)NC1=CC=C(C2=NC(N3[C@@H](C)COCC3)=C(CS4(=O)=O)C(CC4)=N2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)