Malformin A1
Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9.
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- CAS No.: 3022-92-2
- 화학식: C23H39N5O5S2
- 분자량:529.72
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | IC50 |
0.76 μM
Compound: 1; synthetic
|
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27680590] |
| U-937 | IC50 |
0.8 μM
Compound: 1; natural
|
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27680590] |
Chemical Information
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CAS No. 3022-92-2
-
분자량 529.72
-
화학식 C23H39N5O5S2
-
Sequence Shortening
CCVLI (Disulfide bridge:Cys1-Cys2)
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)