3022-92-2
Chemical Structure
Malformin A1
- No. CAS: 3022-92-2
- Formula:C23H39N5O5S2
- Molecular Weight:529.72
InChIKey: RNCGDQLZIATDOU-ZDRBWGSPSA-N
SMILES: O=C1[C@@]([H])(NC([C@H](NC([C@@H](NC([C@@H]2NC([C@H](N1)CSSC2)=O)=O)C(C)C)=O)CC(C)C)=O)[C@H](CC)C
Biological Activity: Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9[1].
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Malformin A1 | Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9. | |||||||||||||||||||||
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Keywords