SYAF080
SYAF080 is a human A₂B adenosine receptor (hA₂B AdoR) antagonist with a Ki of 23.6 nM and a KB of 25.2 nM. SYAF080no relevant inhibition of human CYP450 cytochromes. SYAF080 can be used for the research of inflammation, metabolic and cardiovascular disease.
For research use only. We do not sell to patients.
- CAS No.: 352692-70-7
- Formula: C12H14N2O3S
- Molecular Weight:266.32
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Adenosine Receptor Isoforms
More
Biological Activity
|
hA2B 23.6 nM (Ki) |
hA2B 25.2 nM (Kb) |
SYAF080 (Compound 21a) (10 µM) inhibits hA1, hA2A, hA2B and hA3 (Ki = 23.6 nM for hA2B; KB = 25.2 nM) and inhibits c-AMP production[1].
SYAF080 shows no relevant inhibition of human CYP450 cytochrome[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 352692-70-7
-
Molecular Weight 266.32
-
Formula C12H14N2O3S
-
SMILES
O=C(OCC)C1=C(NC(=O)NC1C2=CSC=C2)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz